Ensemble and single-molecule dynamics of IFT dynein in Caenorhabditis elegans cilia

Cytoplasmic dynein 2 drives retrograde intraflagellar transport but little is known about its dynamics. Here the authors use fluorescence microscopy to track labelled dynein 2 inC. elegansat the single-molecule level and report diffusion at the ciliary base, and pausing and directional switches alon...

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Autores principales:	Jona Mijalkovic, Bram Prevo, Felix Oswald, Pierre Mangeol, Erwin J. G. Peterman
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/7243c05779d643c8b88afa8fc50872de
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spelling	oai:doaj.org-article:7243c05779d643c8b88afa8fc50872de2021-12-02T14:41:10ZEnsemble and single-molecule dynamics of IFT dynein in Caenorhabditis elegans cilia10.1038/ncomms145912041-1723https://doaj.org/article/7243c05779d643c8b88afa8fc50872de2017-02-01T00:00:00Zhttps://doi.org/10.1038/ncomms14591https://doaj.org/toc/2041-1723Cytoplasmic dynein 2 drives retrograde intraflagellar transport but little is known about its dynamics. Here the authors use fluorescence microscopy to track labelled dynein 2 inC. elegansat the single-molecule level and report diffusion at the ciliary base, and pausing and directional switches along the cilium.Jona MijalkovicBram PrevoFelix OswaldPierre MangeolErwin J. G. PetermanNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jona Mijalkovic Bram Prevo Felix Oswald Pierre Mangeol Erwin J. G. Peterman Ensemble and single-molecule dynamics of IFT dynein in Caenorhabditis elegans cilia
description	Cytoplasmic dynein 2 drives retrograde intraflagellar transport but little is known about its dynamics. Here the authors use fluorescence microscopy to track labelled dynein 2 inC. elegansat the single-molecule level and report diffusion at the ciliary base, and pausing and directional switches along the cilium.
format	article
author	Jona Mijalkovic Bram Prevo Felix Oswald Pierre Mangeol Erwin J. G. Peterman
author_facet	Jona Mijalkovic Bram Prevo Felix Oswald Pierre Mangeol Erwin J. G. Peterman
author_sort	Jona Mijalkovic
title	Ensemble and single-molecule dynamics of IFT dynein in Caenorhabditis elegans cilia
title_short	Ensemble and single-molecule dynamics of IFT dynein in Caenorhabditis elegans cilia
title_full	Ensemble and single-molecule dynamics of IFT dynein in Caenorhabditis elegans cilia
title_fullStr	Ensemble and single-molecule dynamics of IFT dynein in Caenorhabditis elegans cilia
title_full_unstemmed	Ensemble and single-molecule dynamics of IFT dynein in Caenorhabditis elegans cilia
title_sort	ensemble and single-molecule dynamics of ift dynein in caenorhabditis elegans cilia
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/7243c05779d643c8b88afa8fc50872de
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Ensemble and single-molecule dynamics of IFT dynein in Caenorhabditis elegans cilia

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