Ensemble and single-molecule dynamics of IFT dynein in Caenorhabditis elegans cilia

Ensemble and single-molecule dynamics of IFT dynein in Caenorhabditis elegans cilia

Cytoplasmic dynein 2 drives retrograde intraflagellar transport but little is known about its dynamics. Here the authors use fluorescence microscopy to track labelled dynein 2 inC. elegansat the single-molecule level and report diffusion at the ciliary base, and pausing and directional switches alon...

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Autores principales: Jona Mijalkovic, Bram Prevo, Felix Oswald, Pierre Mangeol, Erwin J. G. Peterman
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/7243c05779d643c8b88afa8fc50872de
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