Integrated analysis of telomerase enzymatic activity unravels an association with cancer stemness and proliferation

Telomerase activity correlates with distinct cell states, but can be challenging to quantify. Here the authors quantify telomerase activity across a range of biological samples using the expression of 13 genes, and show it correlates with cancer cell proliferation and stemness.

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Detalles Bibliográficos
Autores principales: Nighat Noureen, Shaofang Wu, Yingli Lv, Juechen Yang, W. K. Alfred Yung, Jonathan Gelfond, Xiaojing Wang, Dimpy Koul, Andrew Ludlow, Siyuan Zheng
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/724dd20ce70c4007ae4d8becee60fbbd
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