Activation of the Host Immune Response in <i>Hyphantria cunea</i> (Drury) (Lepidoptera: Noctuidae) Induced by <i>Serratia marcescens</i> Bizio
Host–pathogen interactions are essential to our understanding of biological pesticides. <i>Hyphantria cunea</i> (Drury) is an important forest pest worldwide. The immune mechanism of the interaction between <i>H. cunea</i> and <i>Serratia marcescens</i> Bizio (SM1...
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| Autores principales: | , , , |
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| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
MDPI AG
2021
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/72591dfd3f6c4e3f980e1c559da6e270 |
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| Sumario: | Host–pathogen interactions are essential to our understanding of biological pesticides. <i>Hyphantria cunea</i> (Drury) is an important forest pest worldwide. The immune mechanism of the interaction between <i>H. cunea</i> and <i>Serratia marcescens</i> Bizio (SM1) is unclear. First, transcriptome sequencing and quantitative real-time PCR (qRT-PCR) analysis described the <i>H. cunea</i> immune response to SM1. A total of 234 immune-related differentially expressed genes (DEGs) were found. Many immune regulatory genes in three classical pathways were found. Antimicrobial peptides, including attacin B, cecropin A, gloverin, lebocin and diapausin, are involved in defending against SM1 challenge, and are mainly produced by Toll and immune deficiency (IMD) pathways. Some melanization genes were changed in <i>H. cunea</i>, which suggested that <i>H. cunea</i> melanization was activated by SM1. Furthermore, phagocytosis, autophagolysosome and apoptosis pathways in cellular immunity were activated in <i>H. cunea</i> against SM1. Finally, the expression patterns of 10 immune genes were analyzed systematically by qRT-PCR, and most of the genes were upregulated compared to the control. Our studies provide useful information about the immune response of <i>H. cunea</i> under the stress of SM1, which is important to understand how SM1 affects the immune system of <i>H. cunea</i> and provides new ideas to control <i>H. cunea</i> by using SM1. |
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