Single-cell RNA sequencing highlights the role of inflammatory cancer-associated fibroblasts in bladder urothelial carcinoma

Bladder urothelial carcinoma is one of the most prevalent urogenital cancer types with limited therapeutic options. Here, the authors characterize the tumor immune microenvironment of bladder cancer using single cell RNA sequencing and suggest a role for inflammatory cancer-associated fibroblasts in...

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Autores principales:	Zhaohui Chen, Lijie Zhou, Lilong Liu, Yaxin Hou, Ming Xiong, Yu Yang, Junyi Hu, Ke Chen
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/7259a28520d04855820dd631539f0516
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spelling	oai:doaj.org-article:7259a28520d04855820dd631539f05162021-12-02T19:16:29ZSingle-cell RNA sequencing highlights the role of inflammatory cancer-associated fibroblasts in bladder urothelial carcinoma10.1038/s41467-020-18916-52041-1723https://doaj.org/article/7259a28520d04855820dd631539f05162020-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18916-5https://doaj.org/toc/2041-1723Bladder urothelial carcinoma is one of the most prevalent urogenital cancer types with limited therapeutic options. Here, the authors characterize the tumor immune microenvironment of bladder cancer using single cell RNA sequencing and suggest a role for inflammatory cancer-associated fibroblasts in tumor progression.Zhaohui ChenLijie ZhouLilong LiuYaxin HouMing XiongYu YangJunyi HuKe ChenNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Zhaohui Chen Lijie Zhou Lilong Liu Yaxin Hou Ming Xiong Yu Yang Junyi Hu Ke Chen Single-cell RNA sequencing highlights the role of inflammatory cancer-associated fibroblasts in bladder urothelial carcinoma
description	Bladder urothelial carcinoma is one of the most prevalent urogenital cancer types with limited therapeutic options. Here, the authors characterize the tumor immune microenvironment of bladder cancer using single cell RNA sequencing and suggest a role for inflammatory cancer-associated fibroblasts in tumor progression.
format	article
author	Zhaohui Chen Lijie Zhou Lilong Liu Yaxin Hou Ming Xiong Yu Yang Junyi Hu Ke Chen
author_facet	Zhaohui Chen Lijie Zhou Lilong Liu Yaxin Hou Ming Xiong Yu Yang Junyi Hu Ke Chen
author_sort	Zhaohui Chen
title	Single-cell RNA sequencing highlights the role of inflammatory cancer-associated fibroblasts in bladder urothelial carcinoma
title_short	Single-cell RNA sequencing highlights the role of inflammatory cancer-associated fibroblasts in bladder urothelial carcinoma
title_full	Single-cell RNA sequencing highlights the role of inflammatory cancer-associated fibroblasts in bladder urothelial carcinoma
title_fullStr	Single-cell RNA sequencing highlights the role of inflammatory cancer-associated fibroblasts in bladder urothelial carcinoma
title_full_unstemmed	Single-cell RNA sequencing highlights the role of inflammatory cancer-associated fibroblasts in bladder urothelial carcinoma
title_sort	single-cell rna sequencing highlights the role of inflammatory cancer-associated fibroblasts in bladder urothelial carcinoma
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/7259a28520d04855820dd631539f0516
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Single-cell RNA sequencing highlights the role of inflammatory cancer-associated fibroblasts in bladder urothelial carcinoma

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