Stimulus phase locking of cortical oscillation for auditory stream segregation in rats.

The phase of cortical oscillations contains rich information and is valuable for encoding sound stimuli. Here we hypothesized that oscillatory phase modulation, instead of amplitude modulation, is a neural correlate of auditory streaming. Our behavioral evaluation provided compelling evidences for t...

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Autores principales:	Takahiro Noda, Ryohei Kanzaki, Hirokazu Takahashi
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2013
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/72655581e93b4473aa98b643cebd7384
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spelling	oai:doaj.org-article:72655581e93b4473aa98b643cebd73842021-11-18T08:40:52ZStimulus phase locking of cortical oscillation for auditory stream segregation in rats.1932-620310.1371/journal.pone.0083544https://doaj.org/article/72655581e93b4473aa98b643cebd73842013-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24376715/pdf/?tool=EBIhttps://doaj.org/toc/1932-6203The phase of cortical oscillations contains rich information and is valuable for encoding sound stimuli. Here we hypothesized that oscillatory phase modulation, instead of amplitude modulation, is a neural correlate of auditory streaming. Our behavioral evaluation provided compelling evidences for the first time that rats are able to organize auditory stream. Local field potentials (LFPs) were investigated in the cortical layer IV or deeper in the primary auditory cortex of anesthetized rats. In response to ABA- sequences with different inter-tone intervals and frequency differences, neurometric functions were characterized with phase locking as well as the band-specific amplitude evoked by test tones. Our results demonstrated that under large frequency differences and short inter-tone intervals, the neurometric function based on stimulus phase locking in higher frequency bands, particularly the gamma band, could better describe van Noorden's perceptual boundary than the LFP amplitude. Furthermore, the gamma-band neurometric function showed a build-up-like effect within around 3 seconds from sequence onset. These findings suggest that phase locking and amplitude have different roles in neural computation, and support our hypothesis that temporal modulation of cortical oscillations should be considered to be neurophysiological mechanisms of auditory streaming, in addition to forward suppression, tonotopic separation, and multi-second adaptation.Takahiro NodaRyohei KanzakiHirokazu TakahashiPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 8, Iss 12, p e83544 (2013)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Takahiro Noda Ryohei Kanzaki Hirokazu Takahashi Stimulus phase locking of cortical oscillation for auditory stream segregation in rats.
description	The phase of cortical oscillations contains rich information and is valuable for encoding sound stimuli. Here we hypothesized that oscillatory phase modulation, instead of amplitude modulation, is a neural correlate of auditory streaming. Our behavioral evaluation provided compelling evidences for the first time that rats are able to organize auditory stream. Local field potentials (LFPs) were investigated in the cortical layer IV or deeper in the primary auditory cortex of anesthetized rats. In response to ABA- sequences with different inter-tone intervals and frequency differences, neurometric functions were characterized with phase locking as well as the band-specific amplitude evoked by test tones. Our results demonstrated that under large frequency differences and short inter-tone intervals, the neurometric function based on stimulus phase locking in higher frequency bands, particularly the gamma band, could better describe van Noorden's perceptual boundary than the LFP amplitude. Furthermore, the gamma-band neurometric function showed a build-up-like effect within around 3 seconds from sequence onset. These findings suggest that phase locking and amplitude have different roles in neural computation, and support our hypothesis that temporal modulation of cortical oscillations should be considered to be neurophysiological mechanisms of auditory streaming, in addition to forward suppression, tonotopic separation, and multi-second adaptation.
format	article
author	Takahiro Noda Ryohei Kanzaki Hirokazu Takahashi
author_facet	Takahiro Noda Ryohei Kanzaki Hirokazu Takahashi
author_sort	Takahiro Noda
title	Stimulus phase locking of cortical oscillation for auditory stream segregation in rats.
title_short	Stimulus phase locking of cortical oscillation for auditory stream segregation in rats.
title_full	Stimulus phase locking of cortical oscillation for auditory stream segregation in rats.
title_fullStr	Stimulus phase locking of cortical oscillation for auditory stream segregation in rats.
title_full_unstemmed	Stimulus phase locking of cortical oscillation for auditory stream segregation in rats.
title_sort	stimulus phase locking of cortical oscillation for auditory stream segregation in rats.
publisher	Public Library of Science (PLoS)
publishDate	2013
url	https://doaj.org/article/72655581e93b4473aa98b643cebd7384
work_keys_str_mv	AT takahironoda stimulusphaselockingofcorticaloscillationforauditorystreamsegregationinrats AT ryoheikanzaki stimulusphaselockingofcorticaloscillationforauditorystreamsegregationinrats AT hirokazutakahashi stimulusphaselockingofcorticaloscillationforauditorystreamsegregationinrats
_version_	1718421451389796352

Stimulus phase locking of cortical oscillation for auditory stream segregation in rats.

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