3D collagen architecture induces a conserved migratory and transcriptional response linked to vasculogenic mimicry

Extracellular matrix plays a central role in driving cancer development. Here the authors using an in vitro approach show that confining collagen architectures induce fast and persistent cell migration and the formation of multicellular network structures linked to vascular mimicry observed in tumou...

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Autores principales:	D. O. Velez, B. Tsui, T. Goshia, C. L. Chute, A. Han, H. Carter, S. I. Fraley
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/7281edebafed4bc6a722ce6912c7287f
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spelling	oai:doaj.org-article:7281edebafed4bc6a722ce6912c7287f2021-12-02T15:39:01Z3D collagen architecture induces a conserved migratory and transcriptional response linked to vasculogenic mimicry10.1038/s41467-017-01556-72041-1723https://doaj.org/article/7281edebafed4bc6a722ce6912c7287f2017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01556-7https://doaj.org/toc/2041-1723Extracellular matrix plays a central role in driving cancer development. Here the authors using an in vitro approach show that confining collagen architectures induce fast and persistent cell migration and the formation of multicellular network structures linked to vascular mimicry observed in tumours from patients.D. O. VelezB. TsuiT. GoshiaC. L. ChuteA. HanH. CarterS. I. FraleyNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q D. O. Velez B. Tsui T. Goshia C. L. Chute A. Han H. Carter S. I. Fraley 3D collagen architecture induces a conserved migratory and transcriptional response linked to vasculogenic mimicry
description	Extracellular matrix plays a central role in driving cancer development. Here the authors using an in vitro approach show that confining collagen architectures induce fast and persistent cell migration and the formation of multicellular network structures linked to vascular mimicry observed in tumours from patients.
format	article
author	D. O. Velez B. Tsui T. Goshia C. L. Chute A. Han H. Carter S. I. Fraley
author_facet	D. O. Velez B. Tsui T. Goshia C. L. Chute A. Han H. Carter S. I. Fraley
author_sort	D. O. Velez
title	3D collagen architecture induces a conserved migratory and transcriptional response linked to vasculogenic mimicry
title_short	3D collagen architecture induces a conserved migratory and transcriptional response linked to vasculogenic mimicry
title_full	3D collagen architecture induces a conserved migratory and transcriptional response linked to vasculogenic mimicry
title_fullStr	3D collagen architecture induces a conserved migratory and transcriptional response linked to vasculogenic mimicry
title_full_unstemmed	3D collagen architecture induces a conserved migratory and transcriptional response linked to vasculogenic mimicry
title_sort	3d collagen architecture induces a conserved migratory and transcriptional response linked to vasculogenic mimicry
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/7281edebafed4bc6a722ce6912c7287f
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3D collagen architecture induces a conserved migratory and transcriptional response linked to vasculogenic mimicry

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