3D collagen architecture induces a conserved migratory and transcriptional response linked to vasculogenic mimicry

Extracellular matrix plays a central role in driving cancer development. Here the authors using an in vitro approach show that confining collagen architectures induce fast and persistent cell migration and the formation of multicellular network structures linked to vascular mimicry observed in tumou...

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Autores principales: D. O. Velez, B. Tsui, T. Goshia, C. L. Chute, A. Han, H. Carter, S. I. Fraley
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/7281edebafed4bc6a722ce6912c7287f
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