Concurrent central diabetes insipidus and cerebral salt wasting disease in a post-operative case of craniopharyngioma: a case report

Abstract Background Water and electrolyte disorders commonly encountered in children post-surgery involving hypothalamus and posterior pituitary, are central diabetes insipidus, syndrome of inappropriate secretion of anti-diuretic hormone and cerebral salt wasting disease. Delayed diagnosis and inad...

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Autores principales: Patel Zeeshan Jameel, Sham Lohiya, Keta Vagha, Tauheed Ahmed, Divya Pujari, Jayant Vagha, Ashish Varma
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Publicado: BMC 2021
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Acceso en línea:https://doaj.org/article/728c4cc5ce47400bb6ffb437b8bd841c
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spelling oai:doaj.org-article:728c4cc5ce47400bb6ffb437b8bd841c2021-11-14T12:33:23ZConcurrent central diabetes insipidus and cerebral salt wasting disease in a post-operative case of craniopharyngioma: a case report10.1186/s12887-021-02982-91471-2431https://doaj.org/article/728c4cc5ce47400bb6ffb437b8bd841c2021-11-01T00:00:00Zhttps://doi.org/10.1186/s12887-021-02982-9https://doaj.org/toc/1471-2431Abstract Background Water and electrolyte disorders commonly encountered in children post-surgery involving hypothalamus and posterior pituitary, are central diabetes insipidus, syndrome of inappropriate secretion of anti-diuretic hormone and cerebral salt wasting disease. Delayed diagnosis and inadequate management of such cases may lead to worsened neurological outcomes with a high mortality rate. Case presentation Here we report the case of a 7-year-old girl who underwent surgical resection of a craniopharyngioma, following which she initially developed central diabetes insipidus. However, later on in the course of her illness she developed symptomatic hyponatremia with natriuresis which was diagnosed to be due to cerebral salt wasting disease. This combination of central diabetes insipidus and cerebral salt wasting syndrome is a rare occurrence and poses a diagnostic challenge. Diagnosis and management can be even more difficult when these conditions precede or coexist with each other. Conclusion In such cases development of hyponatremia should always prompt consideration of unusual causes like cerebral salt wasting disease in addition to the classically described syndrome of inappropriate secretion of anti-diuretic hormone. Hence, a thorough knowledge of these disorders along with intensive monitoring of fluid and sodium status is critical for timely diagnosis and management of these patients.Patel Zeeshan JameelSham LohiyaKeta VaghaTauheed AhmedDivya PujariJayant VaghaAshish VarmaBMCarticleCentral diabetes insipidusCerebral salt wasting diseaseCraniopharyngiomaPediatricsRJ1-570ENBMC Pediatrics, Vol 21, Iss 1, Pp 1-6 (2021)
institution DOAJ
collection DOAJ
language EN
topic Central diabetes insipidus
Cerebral salt wasting disease
Craniopharyngioma
Pediatrics
RJ1-570
spellingShingle Central diabetes insipidus
Cerebral salt wasting disease
Craniopharyngioma
Pediatrics
RJ1-570
Patel Zeeshan Jameel
Sham Lohiya
Keta Vagha
Tauheed Ahmed
Divya Pujari
Jayant Vagha
Ashish Varma
Concurrent central diabetes insipidus and cerebral salt wasting disease in a post-operative case of craniopharyngioma: a case report
description Abstract Background Water and electrolyte disorders commonly encountered in children post-surgery involving hypothalamus and posterior pituitary, are central diabetes insipidus, syndrome of inappropriate secretion of anti-diuretic hormone and cerebral salt wasting disease. Delayed diagnosis and inadequate management of such cases may lead to worsened neurological outcomes with a high mortality rate. Case presentation Here we report the case of a 7-year-old girl who underwent surgical resection of a craniopharyngioma, following which she initially developed central diabetes insipidus. However, later on in the course of her illness she developed symptomatic hyponatremia with natriuresis which was diagnosed to be due to cerebral salt wasting disease. This combination of central diabetes insipidus and cerebral salt wasting syndrome is a rare occurrence and poses a diagnostic challenge. Diagnosis and management can be even more difficult when these conditions precede or coexist with each other. Conclusion In such cases development of hyponatremia should always prompt consideration of unusual causes like cerebral salt wasting disease in addition to the classically described syndrome of inappropriate secretion of anti-diuretic hormone. Hence, a thorough knowledge of these disorders along with intensive monitoring of fluid and sodium status is critical for timely diagnosis and management of these patients.
format article
author Patel Zeeshan Jameel
Sham Lohiya
Keta Vagha
Tauheed Ahmed
Divya Pujari
Jayant Vagha
Ashish Varma
author_facet Patel Zeeshan Jameel
Sham Lohiya
Keta Vagha
Tauheed Ahmed
Divya Pujari
Jayant Vagha
Ashish Varma
author_sort Patel Zeeshan Jameel
title Concurrent central diabetes insipidus and cerebral salt wasting disease in a post-operative case of craniopharyngioma: a case report
title_short Concurrent central diabetes insipidus and cerebral salt wasting disease in a post-operative case of craniopharyngioma: a case report
title_full Concurrent central diabetes insipidus and cerebral salt wasting disease in a post-operative case of craniopharyngioma: a case report
title_fullStr Concurrent central diabetes insipidus and cerebral salt wasting disease in a post-operative case of craniopharyngioma: a case report
title_full_unstemmed Concurrent central diabetes insipidus and cerebral salt wasting disease in a post-operative case of craniopharyngioma: a case report
title_sort concurrent central diabetes insipidus and cerebral salt wasting disease in a post-operative case of craniopharyngioma: a case report
publisher BMC
publishDate 2021
url https://doaj.org/article/728c4cc5ce47400bb6ffb437b8bd841c
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