An endothelial activin A-bone morphogenetic protein receptor type 2 link is overdriven in pulmonary hypertension

Pulmonary arterial hypertension is a progressive fatal disease characterized by pathological pulmonary artery remodeling. Here the authors show that the dysregulation of the activin A-bone morphogenetic protein receptor type 2 link in the endothelium is involved in the progression of pulmonary hyper...

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Autores principales: Gusty R. T. Ryanto, Koji Ikeda, Kazuya Miyagawa, Ly Tu, Christophe Guignabert, Marc Humbert, Tomoyuki Fujiyama, Masashi Yanagisawa, Ken-ichi Hirata, Noriaki Emoto
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Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/728f1b45db854296bbbfe58a3c54de8f
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spelling oai:doaj.org-article:728f1b45db854296bbbfe58a3c54de8f2021-12-02T11:39:46ZAn endothelial activin A-bone morphogenetic protein receptor type 2 link is overdriven in pulmonary hypertension10.1038/s41467-021-21961-32041-1723https://doaj.org/article/728f1b45db854296bbbfe58a3c54de8f2021-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21961-3https://doaj.org/toc/2041-1723Pulmonary arterial hypertension is a progressive fatal disease characterized by pathological pulmonary artery remodeling. Here the authors show that the dysregulation of the activin A-bone morphogenetic protein receptor type 2 link in the endothelium is involved in the progression of pulmonary hypertension.Gusty R. T. RyantoKoji IkedaKazuya MiyagawaLy TuChristophe GuignabertMarc HumbertTomoyuki FujiyamaMasashi YanagisawaKen-ichi HirataNoriaki EmotoNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Gusty R. T. Ryanto
Koji Ikeda
Kazuya Miyagawa
Ly Tu
Christophe Guignabert
Marc Humbert
Tomoyuki Fujiyama
Masashi Yanagisawa
Ken-ichi Hirata
Noriaki Emoto
An endothelial activin A-bone morphogenetic protein receptor type 2 link is overdriven in pulmonary hypertension
description Pulmonary arterial hypertension is a progressive fatal disease characterized by pathological pulmonary artery remodeling. Here the authors show that the dysregulation of the activin A-bone morphogenetic protein receptor type 2 link in the endothelium is involved in the progression of pulmonary hypertension.
format article
author Gusty R. T. Ryanto
Koji Ikeda
Kazuya Miyagawa
Ly Tu
Christophe Guignabert
Marc Humbert
Tomoyuki Fujiyama
Masashi Yanagisawa
Ken-ichi Hirata
Noriaki Emoto
author_facet Gusty R. T. Ryanto
Koji Ikeda
Kazuya Miyagawa
Ly Tu
Christophe Guignabert
Marc Humbert
Tomoyuki Fujiyama
Masashi Yanagisawa
Ken-ichi Hirata
Noriaki Emoto
author_sort Gusty R. T. Ryanto
title An endothelial activin A-bone morphogenetic protein receptor type 2 link is overdriven in pulmonary hypertension
title_short An endothelial activin A-bone morphogenetic protein receptor type 2 link is overdriven in pulmonary hypertension
title_full An endothelial activin A-bone morphogenetic protein receptor type 2 link is overdriven in pulmonary hypertension
title_fullStr An endothelial activin A-bone morphogenetic protein receptor type 2 link is overdriven in pulmonary hypertension
title_full_unstemmed An endothelial activin A-bone morphogenetic protein receptor type 2 link is overdriven in pulmonary hypertension
title_sort endothelial activin a-bone morphogenetic protein receptor type 2 link is overdriven in pulmonary hypertension
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/728f1b45db854296bbbfe58a3c54de8f
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