Polyketide Starter and Extender Units Serve as Regulatory Ligands to Coordinate the Biosynthesis of Antibiotics in Actinomycetes

Numerous antibiotics are derived from polyketides, whose biosynthesis is accurately controlled by transcriptional regulators that respond to diverse physiological or environmental signals. It is generally accepted that antibiotics or biosynthetic intermediates serve as effectors to modulate their p...

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Autores principales:	Panpan Wu, Ketao Chen, Bowen Li, Yanni Zhang, Hang Wu, Yuhong Chen, Shaohua Ren, Sabir Khan, Lixin Zhang, Buchang Zhang
Formato:	article
Lenguaje:	EN
Publicado:	American Society for Microbiology 2021
Materias:	Microbiology QR1-502
Acceso en línea:	https://doaj.org/article/72937a43d731481a8394b30fd451ead6
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spelling	oai:doaj.org-article:72937a43d731481a8394b30fd451ead62021-11-03T21:52:35ZPolyketide Starter and Extender Units Serve as Regulatory Ligands to Coordinate the Biosynthesis of Antibiotics in Actinomycetes2150-751110.1128/mBio.02298-21https://doaj.org/article/72937a43d731481a8394b30fd451ead62021-10-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.02298-21https://doaj.org/toc/2150-7511 Numerous antibiotics are derived from polyketides, whose biosynthesis is accurately controlled by transcriptional regulators that respond to diverse physiological or environmental signals. It is generally accepted that antibiotics or biosynthetic intermediates serve as effectors to modulate their production in actinomycetes.Panpan WuKetao ChenBowen LiYanni ZhangHang WuYuhong ChenShaohua RenSabir KhanLixin ZhangBuchang ZhangAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmBio, Vol 12, Iss 5 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Microbiology QR1-502
spellingShingle	Microbiology QR1-502 Panpan Wu Ketao Chen Bowen Li Yanni Zhang Hang Wu Yuhong Chen Shaohua Ren Sabir Khan Lixin Zhang Buchang Zhang Polyketide Starter and Extender Units Serve as Regulatory Ligands to Coordinate the Biosynthesis of Antibiotics in Actinomycetes
description	Numerous antibiotics are derived from polyketides, whose biosynthesis is accurately controlled by transcriptional regulators that respond to diverse physiological or environmental signals. It is generally accepted that antibiotics or biosynthetic intermediates serve as effectors to modulate their production in actinomycetes.
format	article
author	Panpan Wu Ketao Chen Bowen Li Yanni Zhang Hang Wu Yuhong Chen Shaohua Ren Sabir Khan Lixin Zhang Buchang Zhang
author_facet	Panpan Wu Ketao Chen Bowen Li Yanni Zhang Hang Wu Yuhong Chen Shaohua Ren Sabir Khan Lixin Zhang Buchang Zhang
author_sort	Panpan Wu
title	Polyketide Starter and Extender Units Serve as Regulatory Ligands to Coordinate the Biosynthesis of Antibiotics in Actinomycetes
title_short	Polyketide Starter and Extender Units Serve as Regulatory Ligands to Coordinate the Biosynthesis of Antibiotics in Actinomycetes
title_full	Polyketide Starter and Extender Units Serve as Regulatory Ligands to Coordinate the Biosynthesis of Antibiotics in Actinomycetes
title_fullStr	Polyketide Starter and Extender Units Serve as Regulatory Ligands to Coordinate the Biosynthesis of Antibiotics in Actinomycetes
title_full_unstemmed	Polyketide Starter and Extender Units Serve as Regulatory Ligands to Coordinate the Biosynthesis of Antibiotics in Actinomycetes
title_sort	polyketide starter and extender units serve as regulatory ligands to coordinate the biosynthesis of antibiotics in actinomycetes
publisher	American Society for Microbiology
publishDate	2021
url	https://doaj.org/article/72937a43d731481a8394b30fd451ead6
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Polyketide Starter and Extender Units Serve as Regulatory Ligands to Coordinate the Biosynthesis of Antibiotics in Actinomycetes

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