Genome-wide association study identifies variation at 6q25.1 associated with survival in multiple myeloma

The prognosis of multiple myeloma patients varies widely. Here, to identify genetic factors associated with differing prognoses, the authors carried out a meta-analysis of four genome-wide association studies and identified a risk variant associated with survival interval.

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Autores principales: David C. Johnson, Niels Weinhold, Jonathan S. Mitchell, Bowang Chen, Martin Kaiser, Dil B. Begum, Jens Hillengass, Uta Bertsch, Walter A. Gregory, David Cairns, Graham H. Jackson, Asta Försti, Jolanta Nickel, Per Hoffmann, Markus M. Nöethen, Owen W. Stephens, Bart Barlogie, Faith E. Davis, Kari Hemminki, Hartmut Goldschmidt, Richard S. Houlston, Gareth J. Morgan
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Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/7295b3d0d9804f8f8eee173bdad4235a
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spelling oai:doaj.org-article:7295b3d0d9804f8f8eee173bdad4235a2021-12-02T14:40:13ZGenome-wide association study identifies variation at 6q25.1 associated with survival in multiple myeloma10.1038/ncomms102902041-1723https://doaj.org/article/7295b3d0d9804f8f8eee173bdad4235a2016-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms10290https://doaj.org/toc/2041-1723The prognosis of multiple myeloma patients varies widely. Here, to identify genetic factors associated with differing prognoses, the authors carried out a meta-analysis of four genome-wide association studies and identified a risk variant associated with survival interval.David C. JohnsonNiels WeinholdJonathan S. MitchellBowang ChenMartin KaiserDil B. BegumJens HillengassUta BertschWalter A. GregoryDavid CairnsGraham H. JacksonAsta FörstiJolanta NickelPer HoffmannMarkus M. NöethenOwen W. StephensBart BarlogieFaith E. DavisKari HemminkiHartmut GoldschmidtRichard S. HoulstonGareth J. MorganNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-7 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
David C. Johnson
Niels Weinhold
Jonathan S. Mitchell
Bowang Chen
Martin Kaiser
Dil B. Begum
Jens Hillengass
Uta Bertsch
Walter A. Gregory
David Cairns
Graham H. Jackson
Asta Försti
Jolanta Nickel
Per Hoffmann
Markus M. Nöethen
Owen W. Stephens
Bart Barlogie
Faith E. Davis
Kari Hemminki
Hartmut Goldschmidt
Richard S. Houlston
Gareth J. Morgan
Genome-wide association study identifies variation at 6q25.1 associated with survival in multiple myeloma
description The prognosis of multiple myeloma patients varies widely. Here, to identify genetic factors associated with differing prognoses, the authors carried out a meta-analysis of four genome-wide association studies and identified a risk variant associated with survival interval.
format article
author David C. Johnson
Niels Weinhold
Jonathan S. Mitchell
Bowang Chen
Martin Kaiser
Dil B. Begum
Jens Hillengass
Uta Bertsch
Walter A. Gregory
David Cairns
Graham H. Jackson
Asta Försti
Jolanta Nickel
Per Hoffmann
Markus M. Nöethen
Owen W. Stephens
Bart Barlogie
Faith E. Davis
Kari Hemminki
Hartmut Goldschmidt
Richard S. Houlston
Gareth J. Morgan
author_facet David C. Johnson
Niels Weinhold
Jonathan S. Mitchell
Bowang Chen
Martin Kaiser
Dil B. Begum
Jens Hillengass
Uta Bertsch
Walter A. Gregory
David Cairns
Graham H. Jackson
Asta Försti
Jolanta Nickel
Per Hoffmann
Markus M. Nöethen
Owen W. Stephens
Bart Barlogie
Faith E. Davis
Kari Hemminki
Hartmut Goldschmidt
Richard S. Houlston
Gareth J. Morgan
author_sort David C. Johnson
title Genome-wide association study identifies variation at 6q25.1 associated with survival in multiple myeloma
title_short Genome-wide association study identifies variation at 6q25.1 associated with survival in multiple myeloma
title_full Genome-wide association study identifies variation at 6q25.1 associated with survival in multiple myeloma
title_fullStr Genome-wide association study identifies variation at 6q25.1 associated with survival in multiple myeloma
title_full_unstemmed Genome-wide association study identifies variation at 6q25.1 associated with survival in multiple myeloma
title_sort genome-wide association study identifies variation at 6q25.1 associated with survival in multiple myeloma
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/7295b3d0d9804f8f8eee173bdad4235a
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