AMG 837: a novel GPR40/FFA1 agonist that enhances insulin secretion and lowers glucose levels in rodents.

Agonists of GPR40 (FFA1) have been proposed as a means to treat type 2 diabetes. Through lead optimization of a high throughput screening hit, we have identified a novel GPR40 agonist called AMG 837. The objective of these studies was to understand the preclinical pharmacological properties of AMG 8...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Daniel C-H Lin, Jane Zhang, Run Zhuang, Frank Li, Kathy Nguyen, Michael Chen, Thanhvien Tran, Edwin Lopez, Jenny Ying Lin Lu, Xiaoyan Nina Li, Liang Tang, George R Tonn, Gayathri Swaminath, Jeff D Reagan, Jin-Long Chen, Hui Tian, Yi-Jyun Lin, Jonathan B Houze, Jian Luo
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2011
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/729ea24e76304c709713d2c9927fb903
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

Sea el primero en dejar un comentario!

AMG 837: a novel GPR40/FFA1 agonist that enhances insulin secretion and lowers glucose levels in rodents.

Ejemplares similares