Modern methods of diagnosing chronic kidney disease in patients with diabetes mellitus

Chronic kidney disease (CKD) is a general concept that involves renal tissue regardless of the aetiology of the leading disease. CKD occurs in one out of every two patients with diabetes mellitus (DM) and appreciably limits the duration and quality of life. CKD can be diagnosed by glomerular filtrat...

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Autores principales: Tatiana N. Markova, Viktoriia V. Sadovskaya, Marina Y. Bespyatova
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RU
Publicado: Endocrinology Research Centre 2017
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Acceso en línea:https://doaj.org/article/729ec10b979e4bb6a3c7e18314d31e5d
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spelling oai:doaj.org-article:729ec10b979e4bb6a3c7e18314d31e5d2021-11-14T09:00:21ZModern methods of diagnosing chronic kidney disease in patients with diabetes mellitus2072-03512072-037810.14341/DM9268https://doaj.org/article/729ec10b979e4bb6a3c7e18314d31e5d2017-12-01T00:00:00Zhttps://www.dia-endojournals.ru/jour/article/view/9268https://doaj.org/toc/2072-0351https://doaj.org/toc/2072-0378Chronic kidney disease (CKD) is a general concept that involves renal tissue regardless of the aetiology of the leading disease. CKD occurs in one out of every two patients with diabetes mellitus (DM) and appreciably limits the duration and quality of life. CKD can be diagnosed by glomerular filtration rate (GFR), which is recognised as the most representative indicator of the quantity and total workload of nephrons. However, the decrease in GFR occurs at an advanced stage of nephropathy and causes irreversible renal damage, which ultimately requires substitutive renal therapy and, thereby, increases the expense. In this regard, clinical trials have been conducted to identify the biomarkers of CKD reflecting renal damage at earlier stages of the disease. This article presents an overview of modern methods for the diagnosis of CKD and preclinical markers of kidney injury in patients with DM.Tatiana N. MarkovaViktoriia V. SadovskayaMarina Y. BespyatovaEndocrinology Research Centrearticlediabetes mellitusdiabetic nephropathiesbiomarkersglomerular filtration rateNutritional diseases. Deficiency diseasesRC620-627ENRUСахарный диабет, Vol 20, Iss 6, Pp 454-460 (2017)
institution DOAJ
collection DOAJ
language EN
RU
topic diabetes mellitus
diabetic nephropathies
biomarkers
glomerular filtration rate
Nutritional diseases. Deficiency diseases
RC620-627
spellingShingle diabetes mellitus
diabetic nephropathies
biomarkers
glomerular filtration rate
Nutritional diseases. Deficiency diseases
RC620-627
Tatiana N. Markova
Viktoriia V. Sadovskaya
Marina Y. Bespyatova
Modern methods of diagnosing chronic kidney disease in patients with diabetes mellitus
description Chronic kidney disease (CKD) is a general concept that involves renal tissue regardless of the aetiology of the leading disease. CKD occurs in one out of every two patients with diabetes mellitus (DM) and appreciably limits the duration and quality of life. CKD can be diagnosed by glomerular filtration rate (GFR), which is recognised as the most representative indicator of the quantity and total workload of nephrons. However, the decrease in GFR occurs at an advanced stage of nephropathy and causes irreversible renal damage, which ultimately requires substitutive renal therapy and, thereby, increases the expense. In this regard, clinical trials have been conducted to identify the biomarkers of CKD reflecting renal damage at earlier stages of the disease. This article presents an overview of modern methods for the diagnosis of CKD and preclinical markers of kidney injury in patients with DM.
format article
author Tatiana N. Markova
Viktoriia V. Sadovskaya
Marina Y. Bespyatova
author_facet Tatiana N. Markova
Viktoriia V. Sadovskaya
Marina Y. Bespyatova
author_sort Tatiana N. Markova
title Modern methods of diagnosing chronic kidney disease in patients with diabetes mellitus
title_short Modern methods of diagnosing chronic kidney disease in patients with diabetes mellitus
title_full Modern methods of diagnosing chronic kidney disease in patients with diabetes mellitus
title_fullStr Modern methods of diagnosing chronic kidney disease in patients with diabetes mellitus
title_full_unstemmed Modern methods of diagnosing chronic kidney disease in patients with diabetes mellitus
title_sort modern methods of diagnosing chronic kidney disease in patients with diabetes mellitus
publisher Endocrinology Research Centre
publishDate 2017
url https://doaj.org/article/729ec10b979e4bb6a3c7e18314d31e5d
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AT viktoriiavsadovskaya modernmethodsofdiagnosingchronickidneydiseaseinpatientswithdiabetesmellitus
AT marinaybespyatova modernmethodsofdiagnosingchronickidneydiseaseinpatientswithdiabetesmellitus
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