Modern methods of diagnosing chronic kidney disease in patients with diabetes mellitus
Chronic kidney disease (CKD) is a general concept that involves renal tissue regardless of the aetiology of the leading disease. CKD occurs in one out of every two patients with diabetes mellitus (DM) and appreciably limits the duration and quality of life. CKD can be diagnosed by glomerular filtrat...
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Endocrinology Research Centre
2017
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oai:doaj.org-article:729ec10b979e4bb6a3c7e18314d31e5d2021-11-14T09:00:21ZModern methods of diagnosing chronic kidney disease in patients with diabetes mellitus2072-03512072-037810.14341/DM9268https://doaj.org/article/729ec10b979e4bb6a3c7e18314d31e5d2017-12-01T00:00:00Zhttps://www.dia-endojournals.ru/jour/article/view/9268https://doaj.org/toc/2072-0351https://doaj.org/toc/2072-0378Chronic kidney disease (CKD) is a general concept that involves renal tissue regardless of the aetiology of the leading disease. CKD occurs in one out of every two patients with diabetes mellitus (DM) and appreciably limits the duration and quality of life. CKD can be diagnosed by glomerular filtration rate (GFR), which is recognised as the most representative indicator of the quantity and total workload of nephrons. However, the decrease in GFR occurs at an advanced stage of nephropathy and causes irreversible renal damage, which ultimately requires substitutive renal therapy and, thereby, increases the expense. In this regard, clinical trials have been conducted to identify the biomarkers of CKD reflecting renal damage at earlier stages of the disease. This article presents an overview of modern methods for the diagnosis of CKD and preclinical markers of kidney injury in patients with DM.Tatiana N. MarkovaViktoriia V. SadovskayaMarina Y. BespyatovaEndocrinology Research Centrearticlediabetes mellitusdiabetic nephropathiesbiomarkersglomerular filtration rateNutritional diseases. Deficiency diseasesRC620-627ENRUСахарный диабет, Vol 20, Iss 6, Pp 454-460 (2017) |
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diabetes mellitus diabetic nephropathies biomarkers glomerular filtration rate Nutritional diseases. Deficiency diseases RC620-627 |
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diabetes mellitus diabetic nephropathies biomarkers glomerular filtration rate Nutritional diseases. Deficiency diseases RC620-627 Tatiana N. Markova Viktoriia V. Sadovskaya Marina Y. Bespyatova Modern methods of diagnosing chronic kidney disease in patients with diabetes mellitus |
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Chronic kidney disease (CKD) is a general concept that involves renal tissue regardless of the aetiology of the leading disease. CKD occurs in one out of every two patients with diabetes mellitus (DM) and appreciably limits the duration and quality of life. CKD can be diagnosed by glomerular filtration rate (GFR), which is recognised as the most representative indicator of the quantity and total workload of nephrons. However, the decrease in GFR occurs at an advanced stage of nephropathy and causes irreversible renal damage, which ultimately requires substitutive renal therapy and, thereby, increases the expense. In this regard, clinical trials have been conducted to identify the biomarkers of CKD reflecting renal damage at earlier stages of the disease. This article presents an overview of modern methods for the diagnosis of CKD and preclinical markers of kidney injury in patients with DM. |
format |
article |
author |
Tatiana N. Markova Viktoriia V. Sadovskaya Marina Y. Bespyatova |
author_facet |
Tatiana N. Markova Viktoriia V. Sadovskaya Marina Y. Bespyatova |
author_sort |
Tatiana N. Markova |
title |
Modern methods of diagnosing chronic kidney disease in patients with diabetes mellitus |
title_short |
Modern methods of diagnosing chronic kidney disease in patients with diabetes mellitus |
title_full |
Modern methods of diagnosing chronic kidney disease in patients with diabetes mellitus |
title_fullStr |
Modern methods of diagnosing chronic kidney disease in patients with diabetes mellitus |
title_full_unstemmed |
Modern methods of diagnosing chronic kidney disease in patients with diabetes mellitus |
title_sort |
modern methods of diagnosing chronic kidney disease in patients with diabetes mellitus |
publisher |
Endocrinology Research Centre |
publishDate |
2017 |
url |
https://doaj.org/article/729ec10b979e4bb6a3c7e18314d31e5d |
work_keys_str_mv |
AT tatiananmarkova modernmethodsofdiagnosingchronickidneydiseaseinpatientswithdiabetesmellitus AT viktoriiavsadovskaya modernmethodsofdiagnosingchronickidneydiseaseinpatientswithdiabetesmellitus AT marinaybespyatova modernmethodsofdiagnosingchronickidneydiseaseinpatientswithdiabetesmellitus |
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1718429538326675456 |