Sex and Transcatheter Aortic Valve Implantation: Impact of Female Sex on Clinical Outcomes

Transcatheter aortic valve implantation (TAVI) has emerged as an alternative treatment for severe symptomatic aortic stenosis in patients who are not suitable for surgery or are at high surgical risk. Approximately 50% of patients undergoing TAVI are female and this is reflected by a higher inclusio...

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Autores principales:	Alessandra Laricchia, Barbara Bellini, Vittorio Romano, Saud Khawaja, Matteo Montorfano, Alaide Chieffo
Formato:	article
Lenguaje:	EN
Publicado:	Radcliffe Medical Media 2019
Materias:	Surgery RD1-811 Diseases of the circulatory (Cardiovascular) system RC666-701
Acceso en línea:	https://doaj.org/article/72a11eca69e7458fb567a320ea1a9954
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spelling	oai:doaj.org-article:72a11eca69e7458fb567a320ea1a99542021-12-04T16:01:57ZSex and Transcatheter Aortic Valve Implantation: Impact of Female Sex on Clinical Outcomes10.15420/icr.2019.07.R11756-14851756-1477https://doaj.org/article/72a11eca69e7458fb567a320ea1a99542019-11-01T00:00:00Zhttps://www.icrjournal.com/articles/Transcatheter-Aortic-Valve-Implantation-Female-Clinical-Outcomeshttps://doaj.org/toc/1756-1477https://doaj.org/toc/1756-1485Transcatheter aortic valve implantation (TAVI) has emerged as an alternative treatment for severe symptomatic aortic stenosis in patients who are not suitable for surgery or are at high surgical risk. Approximately 50% of patients undergoing TAVI are female and this is reflected by a higher inclusion rate of women in TAVI trials. However, women undergoing TAVI have different baseline clinical characteristics in comparison to men, with fewer comorbidities and a more preserved left ventricular ejection fraction. This translates into favourable outcomes after TAVI, despite a higher rate of peri-procedural complications. This article discusses gender differences in terms of presentation, procedural characteristics and post-procedural results in patients with aortic stenosis undergoing TAVI, with particular focus on possible sex-specific factors affecting outcome.Alessandra LaricchiaBarbara BelliniVittorio RomanoSaud KhawajaMatteo MontorfanoAlaide ChieffoRadcliffe Medical MediaarticleSurgeryRD1-811Diseases of the circulatory (Cardiovascular) systemRC666-701ENInterventional Cardiology: Reviews, Research, Resources, Vol 14, Iss 3, Pp 137-141 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Surgery RD1-811 Diseases of the circulatory (Cardiovascular) system RC666-701
spellingShingle	Surgery RD1-811 Diseases of the circulatory (Cardiovascular) system RC666-701 Alessandra Laricchia Barbara Bellini Vittorio Romano Saud Khawaja Matteo Montorfano Alaide Chieffo Sex and Transcatheter Aortic Valve Implantation: Impact of Female Sex on Clinical Outcomes
description	Transcatheter aortic valve implantation (TAVI) has emerged as an alternative treatment for severe symptomatic aortic stenosis in patients who are not suitable for surgery or are at high surgical risk. Approximately 50% of patients undergoing TAVI are female and this is reflected by a higher inclusion rate of women in TAVI trials. However, women undergoing TAVI have different baseline clinical characteristics in comparison to men, with fewer comorbidities and a more preserved left ventricular ejection fraction. This translates into favourable outcomes after TAVI, despite a higher rate of peri-procedural complications. This article discusses gender differences in terms of presentation, procedural characteristics and post-procedural results in patients with aortic stenosis undergoing TAVI, with particular focus on possible sex-specific factors affecting outcome.
format	article
author	Alessandra Laricchia Barbara Bellini Vittorio Romano Saud Khawaja Matteo Montorfano Alaide Chieffo
author_facet	Alessandra Laricchia Barbara Bellini Vittorio Romano Saud Khawaja Matteo Montorfano Alaide Chieffo
author_sort	Alessandra Laricchia
title	Sex and Transcatheter Aortic Valve Implantation: Impact of Female Sex on Clinical Outcomes
title_short	Sex and Transcatheter Aortic Valve Implantation: Impact of Female Sex on Clinical Outcomes
title_full	Sex and Transcatheter Aortic Valve Implantation: Impact of Female Sex on Clinical Outcomes
title_fullStr	Sex and Transcatheter Aortic Valve Implantation: Impact of Female Sex on Clinical Outcomes
title_full_unstemmed	Sex and Transcatheter Aortic Valve Implantation: Impact of Female Sex on Clinical Outcomes
title_sort	sex and transcatheter aortic valve implantation: impact of female sex on clinical outcomes
publisher	Radcliffe Medical Media
publishDate	2019
url	https://doaj.org/article/72a11eca69e7458fb567a320ea1a9954
work_keys_str_mv	AT alessandralaricchia sexandtranscatheteraorticvalveimplantationimpactoffemalesexonclinicaloutcomes AT barbarabellini sexandtranscatheteraorticvalveimplantationimpactoffemalesexonclinicaloutcomes AT vittorioromano sexandtranscatheteraorticvalveimplantationimpactoffemalesexonclinicaloutcomes AT saudkhawaja sexandtranscatheteraorticvalveimplantationimpactoffemalesexonclinicaloutcomes AT matteomontorfano sexandtranscatheteraorticvalveimplantationimpactoffemalesexonclinicaloutcomes AT alaidechieffo sexandtranscatheteraorticvalveimplantationimpactoffemalesexonclinicaloutcomes
_version_	1718372742828392448

Sex and Transcatheter Aortic Valve Implantation: Impact of Female Sex on Clinical Outcomes

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