Drug-induced regulation of target expression.
Drug perturbations of human cells lead to complex responses upon target binding. One of the known mechanisms is a (positive or negative) feedback loop that adjusts the expression level of the respective target protein. To quantify this mechanism systems-wide in an unbiased way, drug-induced differen...
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Auteurs principaux: | , , , , , |
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Format: | article |
Langue: | EN |
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Public Library of Science (PLoS)
2010
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Accès en ligne: | https://doaj.org/article/72a3c901b8714a26a016442b9f7a0740 |
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