Characterization of the multimeric structure of poly(A)-binding protein on a poly(A) tail

Characterization of the multimeric structure of poly(A)-binding protein on a poly(A) tail

Abstract Eukaryotic mature mRNAs possess a poly adenylate tail (poly(A)), to which multiple molecules of poly(A)-binding protein C1 (PABPC1) bind. PABPC1 regulates translation and mRNA metabolism by binding to regulatory proteins. To understand functional mechanism of the regulatory proteins, it is...

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Autores principales: Ryoichi Sawazaki, Shunsuke Imai, Mariko Yokogawa, Nao Hosoda, Shin-ichi Hoshino, Muneyo Mio, Kazuhiro Mio, Ichio Shimada, Masanori Osawa
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/72a8c212de0b4c6b858a335b08566f8e
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