Characterizing the epidemiological transition in Mexico: national and subnational burden of diseases, injuries, and risk factors.

<h4>Background</h4>Rates of diseases and injuries and the effects of their risk factors can have substantial subnational heterogeneity, especially in middle-income countries like Mexico. Subnational analysis of the burden of diseases, injuries, and risk factors can improve characterizati...

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Autores principales: Gretchen Stevens, Rodrigo H Dias, Kevin J A Thomas, Juan A Rivera, Natalie Carvalho, Simón Barquera, Kenneth Hill, Majid Ezzati
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Publicado: Public Library of Science (PLoS) 2008
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spelling oai:doaj.org-article:72aca94747aa4bb4b7754c36de2065b22021-11-25T05:36:55ZCharacterizing the epidemiological transition in Mexico: national and subnational burden of diseases, injuries, and risk factors.1549-12771549-167610.1371/journal.pmed.0050125https://doaj.org/article/72aca94747aa4bb4b7754c36de2065b22008-06-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/18563960/?tool=EBIhttps://doaj.org/toc/1549-1277https://doaj.org/toc/1549-1676<h4>Background</h4>Rates of diseases and injuries and the effects of their risk factors can have substantial subnational heterogeneity, especially in middle-income countries like Mexico. Subnational analysis of the burden of diseases, injuries, and risk factors can improve characterization of the epidemiological transition and identify policy priorities.<h4>Methods and findings</h4>We estimated deaths and loss of healthy life years (measured in disability-adjusted life years [DALYs]) in 2004 from a comprehensive list of diseases and injuries, and 16 major risk factors, by sex and age for Mexico and its states. Data sources included the vital statistics, national censuses, health examination surveys, and published epidemiological studies. Mortality statistics were adjusted for underreporting, misreporting of age at death, and for misclassification and incomparability of cause-of-death assignment. Nationally, noncommunicable diseases caused 75% of total deaths and 68% of total DALYs, with another 14% of deaths and 18% of DALYs caused by undernutrition and communicable, maternal, and perinatal diseases. The leading causes of death were ischemic heart disease, diabetes mellitus, cerebrovascular disease, liver cirrhosis, and road traffic injuries. High body mass index, high blood glucose, and alcohol use were the leading risk factors for disease burden, causing 5.1%, 5.0%, and 7.3% of total burden of disease, respectively. Mexico City had the lowest mortality rates (4.2 per 1,000) and the Southern region the highest (5.0 per 1,000); under-five mortality in the Southern region was nearly twice that of Mexico City. In the Southern region undernutrition and communicable, maternal, and perinatal diseases caused 23% of DALYs; in Chiapas, they caused 29% of DALYs. At the same time, the absolute rates of noncommunicable disease and injury burdens were highest in the Southern region (105 DALYs per 1,000 population versus 97 nationally for noncommunicable diseases; 22 versus 19 for injuries).<h4>Conclusions</h4>Mexico is at an advanced stage in the epidemiologic transition, with the majority of the disease and injury burden from noncommunicable diseases. A unique characteristic of the epidemiological transition in Mexico is that overweight and obesity, high blood glucose, and alcohol use are responsible for larger burden of disease than other noncommunicable disease risks such as tobacco smoking. The Southern region is least advanced in the epidemiological transition and suffers from the largest burden of ill health in all disease and injury groups.Gretchen StevensRodrigo H DiasKevin J A ThomasJuan A RiveraNatalie CarvalhoSimón BarqueraKenneth HillMajid EzzatiPublic Library of Science (PLoS)articleMedicineRENPLoS Medicine, Vol 5, Iss 6, p e125 (2008)
institution DOAJ
collection DOAJ
language EN
topic Medicine
R
spellingShingle Medicine
R
Gretchen Stevens
Rodrigo H Dias
Kevin J A Thomas
Juan A Rivera
Natalie Carvalho
Simón Barquera
Kenneth Hill
Majid Ezzati
Characterizing the epidemiological transition in Mexico: national and subnational burden of diseases, injuries, and risk factors.
description <h4>Background</h4>Rates of diseases and injuries and the effects of their risk factors can have substantial subnational heterogeneity, especially in middle-income countries like Mexico. Subnational analysis of the burden of diseases, injuries, and risk factors can improve characterization of the epidemiological transition and identify policy priorities.<h4>Methods and findings</h4>We estimated deaths and loss of healthy life years (measured in disability-adjusted life years [DALYs]) in 2004 from a comprehensive list of diseases and injuries, and 16 major risk factors, by sex and age for Mexico and its states. Data sources included the vital statistics, national censuses, health examination surveys, and published epidemiological studies. Mortality statistics were adjusted for underreporting, misreporting of age at death, and for misclassification and incomparability of cause-of-death assignment. Nationally, noncommunicable diseases caused 75% of total deaths and 68% of total DALYs, with another 14% of deaths and 18% of DALYs caused by undernutrition and communicable, maternal, and perinatal diseases. The leading causes of death were ischemic heart disease, diabetes mellitus, cerebrovascular disease, liver cirrhosis, and road traffic injuries. High body mass index, high blood glucose, and alcohol use were the leading risk factors for disease burden, causing 5.1%, 5.0%, and 7.3% of total burden of disease, respectively. Mexico City had the lowest mortality rates (4.2 per 1,000) and the Southern region the highest (5.0 per 1,000); under-five mortality in the Southern region was nearly twice that of Mexico City. In the Southern region undernutrition and communicable, maternal, and perinatal diseases caused 23% of DALYs; in Chiapas, they caused 29% of DALYs. At the same time, the absolute rates of noncommunicable disease and injury burdens were highest in the Southern region (105 DALYs per 1,000 population versus 97 nationally for noncommunicable diseases; 22 versus 19 for injuries).<h4>Conclusions</h4>Mexico is at an advanced stage in the epidemiologic transition, with the majority of the disease and injury burden from noncommunicable diseases. A unique characteristic of the epidemiological transition in Mexico is that overweight and obesity, high blood glucose, and alcohol use are responsible for larger burden of disease than other noncommunicable disease risks such as tobacco smoking. The Southern region is least advanced in the epidemiological transition and suffers from the largest burden of ill health in all disease and injury groups.
format article
author Gretchen Stevens
Rodrigo H Dias
Kevin J A Thomas
Juan A Rivera
Natalie Carvalho
Simón Barquera
Kenneth Hill
Majid Ezzati
author_facet Gretchen Stevens
Rodrigo H Dias
Kevin J A Thomas
Juan A Rivera
Natalie Carvalho
Simón Barquera
Kenneth Hill
Majid Ezzati
author_sort Gretchen Stevens
title Characterizing the epidemiological transition in Mexico: national and subnational burden of diseases, injuries, and risk factors.
title_short Characterizing the epidemiological transition in Mexico: national and subnational burden of diseases, injuries, and risk factors.
title_full Characterizing the epidemiological transition in Mexico: national and subnational burden of diseases, injuries, and risk factors.
title_fullStr Characterizing the epidemiological transition in Mexico: national and subnational burden of diseases, injuries, and risk factors.
title_full_unstemmed Characterizing the epidemiological transition in Mexico: national and subnational burden of diseases, injuries, and risk factors.
title_sort characterizing the epidemiological transition in mexico: national and subnational burden of diseases, injuries, and risk factors.
publisher Public Library of Science (PLoS)
publishDate 2008
url https://doaj.org/article/72aca94747aa4bb4b7754c36de2065b2
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