Prognostic Role of Malnutrition Diagnosed by Bioelectrical Impedance Vector Analysis in Older Adults Hospitalized with COVID-19 Pneumonia: A Prospective Study

Background: Little is known on the clinical relevance of the nutritional status and body composition of patients hospitalized with SARS-CoV-2 infection. The aim of our study was to assess the prevalence of malnutrition in patients with COVID-19 pneumonia using bioelectrical impedance vector analysis...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Andrea Da Porto, Carlo Tascini, Maddalena Peghin, Emanuela Sozio, Gianluca Colussi, Viviana Casarsa, Luca Bulfone, Elena Graziano, Chiara De Carlo, Cristiana Catena, Leonardo A. Sechi
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	malnutrition COVID-19 BIVA bioelectrical impedance vector analysis low cellular mass Nutrition. Foods and food supply TX341-641
Acceso en línea:	https://doaj.org/article/72ae1bd226094c9183bc46fd66e18c9b
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:72ae1bd226094c9183bc46fd66e18c9b
record_format	dspace
spelling	oai:doaj.org-article:72ae1bd226094c9183bc46fd66e18c9b2021-11-25T18:36:38ZPrognostic Role of Malnutrition Diagnosed by Bioelectrical Impedance Vector Analysis in Older Adults Hospitalized with COVID-19 Pneumonia: A Prospective Study10.3390/nu131140852072-6643https://doaj.org/article/72ae1bd226094c9183bc46fd66e18c9b2021-11-01T00:00:00Zhttps://www.mdpi.com/2072-6643/13/11/4085https://doaj.org/toc/2072-6643Background: Little is known on the clinical relevance of the nutritional status and body composition of patients hospitalized with SARS-CoV-2 infection. The aim of our study was to assess the prevalence of malnutrition in patients with COVID-19 pneumonia using bioelectrical impedance vector analysis (BIVA), and to evaluate the relationship of their nutritional status with the severity and outcome of disease. Methods: Among 150 consecutive patients who were hospitalized with COVID-19 pneumonia, 37 (24.3%) were classified as malnourished by BIVA, and were followed-up for 60 days from admission. Outcome measures were differences in the need for invasive mechanical ventilation, in-hospital mortality, and the duration of hospital stay in survivors. Results: During 60 days of follow-up, 10 (27%) malnourished patients and 13 (12%) non-malnourished patients required invasive mechanical ventilation (<i>p</i> = 0.023), and 13 (35%) malnourished patients and 9 (8%) non-malnourished patients died (<i>p</i> < 0.001). The average duration of the hospital stay in survivors was longer in patients with malnutrition (18.2 ± 15.7 vs. 13.2 ± 14.8 days, <i>p</i> < 0.001). In survival analyses, mechanical ventilation free (log-rank 7.887, <i>p</i> = 0.050) and overall (log-rank 17.886, <i>p</i> < 0.001) survival were significantly longer in non-malnourished than malnourished patients. The Cox proportional ratio showed that malnutrition was associated with an increased risk of mechanical ventilation (HR 4.375, <i>p</i> = 0.004) and death (HR 4.478, <i>p</i> = 0.004) after adjusting for major confounders such as age, sex, and BMI. Conclusions: Malnutrition diagnosed with BIVA was associated with worse outcomes in hospitalized patients with COVID-19 pneumonia.Andrea Da PortoCarlo TasciniMaddalena PeghinEmanuela SozioGianluca ColussiViviana CasarsaLuca BulfoneElena GrazianoChiara De CarloCristiana CatenaLeonardo A. SechiMDPI AGarticlemalnutritionCOVID-19BIVAbioelectrical impedance vector analysislow cellular massNutrition. Foods and food supplyTX341-641ENNutrients, Vol 13, Iss 4085, p 4085 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	malnutrition COVID-19 BIVA bioelectrical impedance vector analysis low cellular mass Nutrition. Foods and food supply TX341-641
spellingShingle	malnutrition COVID-19 BIVA bioelectrical impedance vector analysis low cellular mass Nutrition. Foods and food supply TX341-641 Andrea Da Porto Carlo Tascini Maddalena Peghin Emanuela Sozio Gianluca Colussi Viviana Casarsa Luca Bulfone Elena Graziano Chiara De Carlo Cristiana Catena Leonardo A. Sechi Prognostic Role of Malnutrition Diagnosed by Bioelectrical Impedance Vector Analysis in Older Adults Hospitalized with COVID-19 Pneumonia: A Prospective Study
description	Background: Little is known on the clinical relevance of the nutritional status and body composition of patients hospitalized with SARS-CoV-2 infection. The aim of our study was to assess the prevalence of malnutrition in patients with COVID-19 pneumonia using bioelectrical impedance vector analysis (BIVA), and to evaluate the relationship of their nutritional status with the severity and outcome of disease. Methods: Among 150 consecutive patients who were hospitalized with COVID-19 pneumonia, 37 (24.3%) were classified as malnourished by BIVA, and were followed-up for 60 days from admission. Outcome measures were differences in the need for invasive mechanical ventilation, in-hospital mortality, and the duration of hospital stay in survivors. Results: During 60 days of follow-up, 10 (27%) malnourished patients and 13 (12%) non-malnourished patients required invasive mechanical ventilation (<i>p</i> = 0.023), and 13 (35%) malnourished patients and 9 (8%) non-malnourished patients died (<i>p</i> < 0.001). The average duration of the hospital stay in survivors was longer in patients with malnutrition (18.2 ± 15.7 vs. 13.2 ± 14.8 days, <i>p</i> < 0.001). In survival analyses, mechanical ventilation free (log-rank 7.887, <i>p</i> = 0.050) and overall (log-rank 17.886, <i>p</i> < 0.001) survival were significantly longer in non-malnourished than malnourished patients. The Cox proportional ratio showed that malnutrition was associated with an increased risk of mechanical ventilation (HR 4.375, <i>p</i> = 0.004) and death (HR 4.478, <i>p</i> = 0.004) after adjusting for major confounders such as age, sex, and BMI. Conclusions: Malnutrition diagnosed with BIVA was associated with worse outcomes in hospitalized patients with COVID-19 pneumonia.
format	article
author	Andrea Da Porto Carlo Tascini Maddalena Peghin Emanuela Sozio Gianluca Colussi Viviana Casarsa Luca Bulfone Elena Graziano Chiara De Carlo Cristiana Catena Leonardo A. Sechi
author_facet	Andrea Da Porto Carlo Tascini Maddalena Peghin Emanuela Sozio Gianluca Colussi Viviana Casarsa Luca Bulfone Elena Graziano Chiara De Carlo Cristiana Catena Leonardo A. Sechi
author_sort	Andrea Da Porto
title	Prognostic Role of Malnutrition Diagnosed by Bioelectrical Impedance Vector Analysis in Older Adults Hospitalized with COVID-19 Pneumonia: A Prospective Study
title_short	Prognostic Role of Malnutrition Diagnosed by Bioelectrical Impedance Vector Analysis in Older Adults Hospitalized with COVID-19 Pneumonia: A Prospective Study
title_full	Prognostic Role of Malnutrition Diagnosed by Bioelectrical Impedance Vector Analysis in Older Adults Hospitalized with COVID-19 Pneumonia: A Prospective Study
title_fullStr	Prognostic Role of Malnutrition Diagnosed by Bioelectrical Impedance Vector Analysis in Older Adults Hospitalized with COVID-19 Pneumonia: A Prospective Study
title_full_unstemmed	Prognostic Role of Malnutrition Diagnosed by Bioelectrical Impedance Vector Analysis in Older Adults Hospitalized with COVID-19 Pneumonia: A Prospective Study
title_sort	prognostic role of malnutrition diagnosed by bioelectrical impedance vector analysis in older adults hospitalized with covid-19 pneumonia: a prospective study
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/72ae1bd226094c9183bc46fd66e18c9b
work_keys_str_mv	AT andreadaporto prognosticroleofmalnutritiondiagnosedbybioelectricalimpedancevectoranalysisinolderadultshospitalizedwithcovid19pneumoniaaprospectivestudy AT carlotascini prognosticroleofmalnutritiondiagnosedbybioelectricalimpedancevectoranalysisinolderadultshospitalizedwithcovid19pneumoniaaprospectivestudy AT maddalenapeghin prognosticroleofmalnutritiondiagnosedbybioelectricalimpedancevectoranalysisinolderadultshospitalizedwithcovid19pneumoniaaprospectivestudy AT emanuelasozio prognosticroleofmalnutritiondiagnosedbybioelectricalimpedancevectoranalysisinolderadultshospitalizedwithcovid19pneumoniaaprospectivestudy AT gianlucacolussi prognosticroleofmalnutritiondiagnosedbybioelectricalimpedancevectoranalysisinolderadultshospitalizedwithcovid19pneumoniaaprospectivestudy AT vivianacasarsa prognosticroleofmalnutritiondiagnosedbybioelectricalimpedancevectoranalysisinolderadultshospitalizedwithcovid19pneumoniaaprospectivestudy AT lucabulfone prognosticroleofmalnutritiondiagnosedbybioelectricalimpedancevectoranalysisinolderadultshospitalizedwithcovid19pneumoniaaprospectivestudy AT elenagraziano prognosticroleofmalnutritiondiagnosedbybioelectricalimpedancevectoranalysisinolderadultshospitalizedwithcovid19pneumoniaaprospectivestudy AT chiaradecarlo prognosticroleofmalnutritiondiagnosedbybioelectricalimpedancevectoranalysisinolderadultshospitalizedwithcovid19pneumoniaaprospectivestudy AT cristianacatena prognosticroleofmalnutritiondiagnosedbybioelectricalimpedancevectoranalysisinolderadultshospitalizedwithcovid19pneumoniaaprospectivestudy AT leonardoasechi prognosticroleofmalnutritiondiagnosedbybioelectricalimpedancevectoranalysisinolderadultshospitalizedwithcovid19pneumoniaaprospectivestudy
_version_	1718410897284661248

Prognostic Role of Malnutrition Diagnosed by Bioelectrical Impedance Vector Analysis in Older Adults Hospitalized with COVID-19 Pneumonia: A Prospective Study

Ejemplares similares