Correlation between Imaging Features and Pathological Stages of Primary Lung Tumors Based on Nanocontrast Agents

As one of the conventional methods of lung cancer detection, computed tomography (CT) usually requires the use of contrast agents to enhance the imaging effect. Conventional iodine contrast agents have poor signal-to-noise ratio and are prone to adverse reactions. It is necessary to find more effect...

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Autores principales:	Jin Li, Qian Xu, Cunhua Mao, Yuliang Liu
Formato:	article
Lenguaje:	EN
Publicado:	Hindawi Limited 2021
Materias:	Computer applications to medicine. Medical informatics R858-859.7
Acceso en línea:	https://doaj.org/article/72afe67dc4b64f598f220694f830cfa4
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spelling	oai:doaj.org-article:72afe67dc4b64f598f220694f830cfa42021-11-22T01:10:55ZCorrelation between Imaging Features and Pathological Stages of Primary Lung Tumors Based on Nanocontrast Agents1748-671810.1155/2021/2343299https://doaj.org/article/72afe67dc4b64f598f220694f830cfa42021-01-01T00:00:00Zhttp://dx.doi.org/10.1155/2021/2343299https://doaj.org/toc/1748-6718As one of the conventional methods of lung cancer detection, computed tomography (CT) usually requires the use of contrast agents to enhance the imaging effect. Conventional iodine contrast agents have poor signal-to-noise ratio and are prone to adverse reactions. It is necessary to find more effective and safe contrast agents for CT scans. The gold nanoparticles with secondary electron effect and photoelectric absorption effect can prolong the display time of the patient’s blood circulation after being injected into the patient’s body, which makes the nanocontrast agent a research hotspot in the field of CT imaging. In this study, ultrasmall gold nanoclusters with a diameter of about 5 nm were used as the contrast agent in CT scans. It was found that CT scans based on nanocontrast agents can obtain high-quality lung cancer imaging images, and the patient has no obvious adverse reactions. When observing the CT image, it was found that the stage of lung cancer patients can be clearly distinguished through the CT scan image. When analyzing the consistency of CT imaging and pathological classification, the Kappa value was 0.810, indicating that the two have a high degree of consistency. Therefore, this study believes that the imaging characteristics of primary lung tumors based on nanocontrast agents are highly correlated with their pathological types.Jin LiQian XuCunhua MaoYuliang LiuHindawi LimitedarticleComputer applications to medicine. Medical informaticsR858-859.7ENComputational and Mathematical Methods in Medicine, Vol 2021 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Computer applications to medicine. Medical informatics R858-859.7
spellingShingle	Computer applications to medicine. Medical informatics R858-859.7 Jin Li Qian Xu Cunhua Mao Yuliang Liu Correlation between Imaging Features and Pathological Stages of Primary Lung Tumors Based on Nanocontrast Agents
description	As one of the conventional methods of lung cancer detection, computed tomography (CT) usually requires the use of contrast agents to enhance the imaging effect. Conventional iodine contrast agents have poor signal-to-noise ratio and are prone to adverse reactions. It is necessary to find more effective and safe contrast agents for CT scans. The gold nanoparticles with secondary electron effect and photoelectric absorption effect can prolong the display time of the patient’s blood circulation after being injected into the patient’s body, which makes the nanocontrast agent a research hotspot in the field of CT imaging. In this study, ultrasmall gold nanoclusters with a diameter of about 5 nm were used as the contrast agent in CT scans. It was found that CT scans based on nanocontrast agents can obtain high-quality lung cancer imaging images, and the patient has no obvious adverse reactions. When observing the CT image, it was found that the stage of lung cancer patients can be clearly distinguished through the CT scan image. When analyzing the consistency of CT imaging and pathological classification, the Kappa value was 0.810, indicating that the two have a high degree of consistency. Therefore, this study believes that the imaging characteristics of primary lung tumors based on nanocontrast agents are highly correlated with their pathological types.
format	article
author	Jin Li Qian Xu Cunhua Mao Yuliang Liu
author_facet	Jin Li Qian Xu Cunhua Mao Yuliang Liu
author_sort	Jin Li
title	Correlation between Imaging Features and Pathological Stages of Primary Lung Tumors Based on Nanocontrast Agents
title_short	Correlation between Imaging Features and Pathological Stages of Primary Lung Tumors Based on Nanocontrast Agents
title_full	Correlation between Imaging Features and Pathological Stages of Primary Lung Tumors Based on Nanocontrast Agents
title_fullStr	Correlation between Imaging Features and Pathological Stages of Primary Lung Tumors Based on Nanocontrast Agents
title_full_unstemmed	Correlation between Imaging Features and Pathological Stages of Primary Lung Tumors Based on Nanocontrast Agents
title_sort	correlation between imaging features and pathological stages of primary lung tumors based on nanocontrast agents
publisher	Hindawi Limited
publishDate	2021
url	https://doaj.org/article/72afe67dc4b64f598f220694f830cfa4
work_keys_str_mv	AT jinli correlationbetweenimagingfeaturesandpathologicalstagesofprimarylungtumorsbasedonnanocontrastagents AT qianxu correlationbetweenimagingfeaturesandpathologicalstagesofprimarylungtumorsbasedonnanocontrastagents AT cunhuamao correlationbetweenimagingfeaturesandpathologicalstagesofprimarylungtumorsbasedonnanocontrastagents AT yuliangliu correlationbetweenimagingfeaturesandpathologicalstagesofprimarylungtumorsbasedonnanocontrastagents
_version_	1718418345485664256

Correlation between Imaging Features and Pathological Stages of Primary Lung Tumors Based on Nanocontrast Agents

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