Non-enzymatic sensor for determination of glucose based on PtNi nanoparticles decorated graphene

Abstract Diabetes has become a universal epidemic in recent years. Herein, the monitoring of glucose in blood is of importance in clinical applications. In this work, PtNi alloy nanoparticles homogeneously dispersed on graphene (PtNi alloy-graphene) was synthesized as a highly effective electrode ma...

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Autores principales:	Risheng Li, Xu Deng, Longfei Xia
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/72b11a334c304f3da7571b7d5ab203da
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spelling	oai:doaj.org-article:72b11a334c304f3da7571b7d5ab203da2021-12-02T18:37:08ZNon-enzymatic sensor for determination of glucose based on PtNi nanoparticles decorated graphene10.1038/s41598-020-73567-22045-2322https://doaj.org/article/72b11a334c304f3da7571b7d5ab203da2020-10-01T00:00:00Zhttps://doi.org/10.1038/s41598-020-73567-2https://doaj.org/toc/2045-2322Abstract Diabetes has become a universal epidemic in recent years. Herein, the monitoring of glucose in blood is of importance in clinical applications. In this work, PtNi alloy nanoparticles homogeneously dispersed on graphene (PtNi alloy-graphene) was synthesized as a highly effective electrode material for glucose detection. Based on the modified PtNi alloy-graphene/glass carbon (PtNi alloy-graphene/GC) electrode, it is found that the PtNi alloy-graphene/GC electrode exhibited excellent electrocatalytic performance on glucose oxidation. Furthermore, the results from amperometric current–time curve show a good linear range of 0.5–15 mM with the limit of detection of 16 uM (S/N = 3) and a high sensitivity of 24.03 uAmM−1 cm−2. On account of the good selectivity and durability, the modified electrode was successfully applied on glucose detection in blood serum samples.Risheng LiXu DengLongfei XiaNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 10, Iss 1, Pp 1-8 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Risheng Li Xu Deng Longfei Xia Non-enzymatic sensor for determination of glucose based on PtNi nanoparticles decorated graphene
description	Abstract Diabetes has become a universal epidemic in recent years. Herein, the monitoring of glucose in blood is of importance in clinical applications. In this work, PtNi alloy nanoparticles homogeneously dispersed on graphene (PtNi alloy-graphene) was synthesized as a highly effective electrode material for glucose detection. Based on the modified PtNi alloy-graphene/glass carbon (PtNi alloy-graphene/GC) electrode, it is found that the PtNi alloy-graphene/GC electrode exhibited excellent electrocatalytic performance on glucose oxidation. Furthermore, the results from amperometric current–time curve show a good linear range of 0.5–15 mM with the limit of detection of 16 uM (S/N = 3) and a high sensitivity of 24.03 uAmM−1 cm−2. On account of the good selectivity and durability, the modified electrode was successfully applied on glucose detection in blood serum samples.
format	article
author	Risheng Li Xu Deng Longfei Xia
author_facet	Risheng Li Xu Deng Longfei Xia
author_sort	Risheng Li
title	Non-enzymatic sensor for determination of glucose based on PtNi nanoparticles decorated graphene
title_short	Non-enzymatic sensor for determination of glucose based on PtNi nanoparticles decorated graphene
title_full	Non-enzymatic sensor for determination of glucose based on PtNi nanoparticles decorated graphene
title_fullStr	Non-enzymatic sensor for determination of glucose based on PtNi nanoparticles decorated graphene
title_full_unstemmed	Non-enzymatic sensor for determination of glucose based on PtNi nanoparticles decorated graphene
title_sort	non-enzymatic sensor for determination of glucose based on ptni nanoparticles decorated graphene
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/72b11a334c304f3da7571b7d5ab203da
work_keys_str_mv	AT rishengli nonenzymaticsensorfordeterminationofglucosebasedonptninanoparticlesdecoratedgraphene AT xudeng nonenzymaticsensorfordeterminationofglucosebasedonptninanoparticlesdecoratedgraphene AT longfeixia nonenzymaticsensorfordeterminationofglucosebasedonptninanoparticlesdecoratedgraphene
_version_	1718377805174013952

Non-enzymatic sensor for determination of glucose based on PtNi nanoparticles decorated graphene

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