Purification of functional human ES and iPSC-derived midbrain dopaminergic progenitors using LRTM1

Midbrain dopaminergic neurons generated from stem cells show promise for the treatment of Parkinson’s disease. Here, the authors use the cell surface marker, LRTM1, to enrich the midbrain dopaminergic progenitors and show improved motor function/cell survival when grafted into rat/monkey brains, res...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Bumpei Samata, Daisuke Doi, Kaneyasu Nishimura, Tetsuhiro Kikuchi, Akira Watanabe, Yoshimasa Sakamoto, Jungo Kakuta, Yuichi Ono, Jun Takahashi
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/72b25ae7a986456d8a439b751da50607
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:72b25ae7a986456d8a439b751da50607
record_format	dspace
spelling	oai:doaj.org-article:72b25ae7a986456d8a439b751da506072021-12-02T14:39:11ZPurification of functional human ES and iPSC-derived midbrain dopaminergic progenitors using LRTM110.1038/ncomms130972041-1723https://doaj.org/article/72b25ae7a986456d8a439b751da506072016-10-01T00:00:00Zhttps://doi.org/10.1038/ncomms13097https://doaj.org/toc/2041-1723Midbrain dopaminergic neurons generated from stem cells show promise for the treatment of Parkinson’s disease. Here, the authors use the cell surface marker, LRTM1, to enrich the midbrain dopaminergic progenitors and show improved motor function/cell survival when grafted into rat/monkey brains, respectively.Bumpei SamataDaisuke DoiKaneyasu NishimuraTetsuhiro KikuchiAkira WatanabeYoshimasa SakamotoJungo KakutaYuichi OnoJun TakahashiNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Bumpei Samata Daisuke Doi Kaneyasu Nishimura Tetsuhiro Kikuchi Akira Watanabe Yoshimasa Sakamoto Jungo Kakuta Yuichi Ono Jun Takahashi Purification of functional human ES and iPSC-derived midbrain dopaminergic progenitors using LRTM1
description	Midbrain dopaminergic neurons generated from stem cells show promise for the treatment of Parkinson’s disease. Here, the authors use the cell surface marker, LRTM1, to enrich the midbrain dopaminergic progenitors and show improved motor function/cell survival when grafted into rat/monkey brains, respectively.
format	article
author	Bumpei Samata Daisuke Doi Kaneyasu Nishimura Tetsuhiro Kikuchi Akira Watanabe Yoshimasa Sakamoto Jungo Kakuta Yuichi Ono Jun Takahashi
author_facet	Bumpei Samata Daisuke Doi Kaneyasu Nishimura Tetsuhiro Kikuchi Akira Watanabe Yoshimasa Sakamoto Jungo Kakuta Yuichi Ono Jun Takahashi
author_sort	Bumpei Samata
title	Purification of functional human ES and iPSC-derived midbrain dopaminergic progenitors using LRTM1
title_short	Purification of functional human ES and iPSC-derived midbrain dopaminergic progenitors using LRTM1
title_full	Purification of functional human ES and iPSC-derived midbrain dopaminergic progenitors using LRTM1
title_fullStr	Purification of functional human ES and iPSC-derived midbrain dopaminergic progenitors using LRTM1
title_full_unstemmed	Purification of functional human ES and iPSC-derived midbrain dopaminergic progenitors using LRTM1
title_sort	purification of functional human es and ipsc-derived midbrain dopaminergic progenitors using lrtm1
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/72b25ae7a986456d8a439b751da50607
work_keys_str_mv	AT bumpeisamata purificationoffunctionalhumanesandipscderivedmidbraindopaminergicprogenitorsusinglrtm1 AT daisukedoi purificationoffunctionalhumanesandipscderivedmidbraindopaminergicprogenitorsusinglrtm1 AT kaneyasunishimura purificationoffunctionalhumanesandipscderivedmidbraindopaminergicprogenitorsusinglrtm1 AT tetsuhirokikuchi purificationoffunctionalhumanesandipscderivedmidbraindopaminergicprogenitorsusinglrtm1 AT akirawatanabe purificationoffunctionalhumanesandipscderivedmidbraindopaminergicprogenitorsusinglrtm1 AT yoshimasasakamoto purificationoffunctionalhumanesandipscderivedmidbraindopaminergicprogenitorsusinglrtm1 AT jungokakuta purificationoffunctionalhumanesandipscderivedmidbraindopaminergicprogenitorsusinglrtm1 AT yuichiono purificationoffunctionalhumanesandipscderivedmidbraindopaminergicprogenitorsusinglrtm1 AT juntakahashi purificationoffunctionalhumanesandipscderivedmidbraindopaminergicprogenitorsusinglrtm1
_version_	1718390720143818752

Purification of functional human ES and iPSC-derived midbrain dopaminergic progenitors using LRTM1

Ejemplares similares