TRAIP/RNF206 is required for recruitment of RAP80 to sites of DNA damage

Recruiting DNA damage repair factors to the sites of DNA damage is critical for the maintenance of genome integrity. Here the authors identify that the TRAF-interacting protein (TRAIP/RNF206) is required for normal recruitment of RAP80 to DNA lesions and the stimulation of homologous recombination.

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Autores principales: Nam Soo Lee, Hee Jin Chung, Hyoung-June Kim, Seo Yun Lee, Jae-Hoon Ji, Yoojeong Seo, Seung Hun Han, Minji Choi, Miyong Yun, Seok-Geun Lee, Kyungjae Myung, Yonghwan Kim, Ho Chul Kang, Hongtae Kim
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Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/72bf4c78c1ad40a48afe36239425d37a
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spelling oai:doaj.org-article:72bf4c78c1ad40a48afe36239425d37a2021-12-02T15:34:11ZTRAIP/RNF206 is required for recruitment of RAP80 to sites of DNA damage10.1038/ncomms104632041-1723https://doaj.org/article/72bf4c78c1ad40a48afe36239425d37a2016-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms10463https://doaj.org/toc/2041-1723Recruiting DNA damage repair factors to the sites of DNA damage is critical for the maintenance of genome integrity. Here the authors identify that the TRAF-interacting protein (TRAIP/RNF206) is required for normal recruitment of RAP80 to DNA lesions and the stimulation of homologous recombination.Nam Soo LeeHee Jin ChungHyoung-June KimSeo Yun LeeJae-Hoon JiYoojeong SeoSeung Hun HanMinji ChoiMiyong YunSeok-Geun LeeKyungjae MyungYonghwan KimHo Chul KangHongtae KimNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Nam Soo Lee
Hee Jin Chung
Hyoung-June Kim
Seo Yun Lee
Jae-Hoon Ji
Yoojeong Seo
Seung Hun Han
Minji Choi
Miyong Yun
Seok-Geun Lee
Kyungjae Myung
Yonghwan Kim
Ho Chul Kang
Hongtae Kim
TRAIP/RNF206 is required for recruitment of RAP80 to sites of DNA damage
description Recruiting DNA damage repair factors to the sites of DNA damage is critical for the maintenance of genome integrity. Here the authors identify that the TRAF-interacting protein (TRAIP/RNF206) is required for normal recruitment of RAP80 to DNA lesions and the stimulation of homologous recombination.
format article
author Nam Soo Lee
Hee Jin Chung
Hyoung-June Kim
Seo Yun Lee
Jae-Hoon Ji
Yoojeong Seo
Seung Hun Han
Minji Choi
Miyong Yun
Seok-Geun Lee
Kyungjae Myung
Yonghwan Kim
Ho Chul Kang
Hongtae Kim
author_facet Nam Soo Lee
Hee Jin Chung
Hyoung-June Kim
Seo Yun Lee
Jae-Hoon Ji
Yoojeong Seo
Seung Hun Han
Minji Choi
Miyong Yun
Seok-Geun Lee
Kyungjae Myung
Yonghwan Kim
Ho Chul Kang
Hongtae Kim
author_sort Nam Soo Lee
title TRAIP/RNF206 is required for recruitment of RAP80 to sites of DNA damage
title_short TRAIP/RNF206 is required for recruitment of RAP80 to sites of DNA damage
title_full TRAIP/RNF206 is required for recruitment of RAP80 to sites of DNA damage
title_fullStr TRAIP/RNF206 is required for recruitment of RAP80 to sites of DNA damage
title_full_unstemmed TRAIP/RNF206 is required for recruitment of RAP80 to sites of DNA damage
title_sort traip/rnf206 is required for recruitment of rap80 to sites of dna damage
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/72bf4c78c1ad40a48afe36239425d37a
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