Host-mediated selection impacts the diversity of Plasmodium falciparum antigens within infections

Host immune responses exert selective pressure on Plasmodium falciparum. Here, the authors show that allele-specific immunity impacts the antigenic diversity of individual malaria infections. This process partially explains the extreme amino acid diversity of many parasite antigens and suggests that...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Angela M. Early, Marc Lievens, Bronwyn L. MacInnis, Christian F. Ockenhouse, Sarah K. Volkman, Samuel Adjei, Tsiri Agbenyega, Daniel Ansong, Stacey Gondi, Brian Greenwood, Mary Hamel, Chris Odero, Kephas Otieno, Walter Otieno, Seth Owusu-Agyei, Kwaku Poku Asante, Hermann Sorgho, Lucas Tina, Halidou Tinto, Innocent Valea, Dyann F. Wirth, Daniel E. Neafsey
Format: article
Langue:EN
Publié: Nature Portfolio 2018
Sujets:
Q
Accès en ligne:https://doaj.org/article/72c34aa44dde4a05811cc3f406231978
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!