An original infection model identifies host lipoprotein import as a route for blood-brain barrier crossing

Bacterial and fungal pathogens that cross the blood-brain-barrier (BBB) can cause severe disease. Here, Benmimoun et al. develop a model to study BBB crossing in the developing Drosophila brain and discover Group B Streptococcus factors important for BBB crossing and virulence, one of which, a lipop...

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Autores principales:	Billel Benmimoun, Florentia Papastefanaki, Bruno Périchon, Katerina Segklia, Nicolas Roby, Vivi Miriagou, Christine Schmitt, Shaynoor Dramsi, Rebecca Matsas, Pauline Spéder
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/72c5e89af82d45ca9b3d23db3fa88bc8
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spelling	oai:doaj.org-article:72c5e89af82d45ca9b3d23db3fa88bc82021-12-02T14:40:50ZAn original infection model identifies host lipoprotein import as a route for blood-brain barrier crossing10.1038/s41467-020-19826-22041-1723https://doaj.org/article/72c5e89af82d45ca9b3d23db3fa88bc82020-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19826-2https://doaj.org/toc/2041-1723Bacterial and fungal pathogens that cross the blood-brain-barrier (BBB) can cause severe disease. Here, Benmimoun et al. develop a model to study BBB crossing in the developing Drosophila brain and discover Group B Streptococcus factors important for BBB crossing and virulence, one of which, a lipoprotein, they confirm in mice.Billel BenmimounFlorentia PapastefanakiBruno PérichonKaterina SegkliaNicolas RobyVivi MiriagouChristine SchmittShaynoor DramsiRebecca MatsasPauline SpéderNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Billel Benmimoun Florentia Papastefanaki Bruno Périchon Katerina Segklia Nicolas Roby Vivi Miriagou Christine Schmitt Shaynoor Dramsi Rebecca Matsas Pauline Spéder An original infection model identifies host lipoprotein import as a route for blood-brain barrier crossing
description	Bacterial and fungal pathogens that cross the blood-brain-barrier (BBB) can cause severe disease. Here, Benmimoun et al. develop a model to study BBB crossing in the developing Drosophila brain and discover Group B Streptococcus factors important for BBB crossing and virulence, one of which, a lipoprotein, they confirm in mice.
format	article
author	Billel Benmimoun Florentia Papastefanaki Bruno Périchon Katerina Segklia Nicolas Roby Vivi Miriagou Christine Schmitt Shaynoor Dramsi Rebecca Matsas Pauline Spéder
author_facet	Billel Benmimoun Florentia Papastefanaki Bruno Périchon Katerina Segklia Nicolas Roby Vivi Miriagou Christine Schmitt Shaynoor Dramsi Rebecca Matsas Pauline Spéder
author_sort	Billel Benmimoun
title	An original infection model identifies host lipoprotein import as a route for blood-brain barrier crossing
title_short	An original infection model identifies host lipoprotein import as a route for blood-brain barrier crossing
title_full	An original infection model identifies host lipoprotein import as a route for blood-brain barrier crossing
title_fullStr	An original infection model identifies host lipoprotein import as a route for blood-brain barrier crossing
title_full_unstemmed	An original infection model identifies host lipoprotein import as a route for blood-brain barrier crossing
title_sort	original infection model identifies host lipoprotein import as a route for blood-brain barrier crossing
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/72c5e89af82d45ca9b3d23db3fa88bc8
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An original infection model identifies host lipoprotein import as a route for blood-brain barrier crossing

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