Immune phenotyping of diverse syngeneic murine brain tumors identifies immunologically distinct types

Syngeneic mouse models for glioblastoma (GBM) cannot fully recapitulate clinical findings and response to therapy in patients. Here the authors perform a comprehensive immune profiling of different syngeneic GBM tumour models and compare it with the immune landscape of GBM patients to identify simil...

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Autores principales:	Jasneet Kaur Khalsa, Nina Cheng, Joshua Keegan, Ameen Chaudry, Joseph Driver, Wenya Linda Bi, James Lederer, Khalid Shah
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/72c638431fd645f4b067eec34075de39
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spelling	oai:doaj.org-article:72c638431fd645f4b067eec34075de392021-12-02T18:49:35ZImmune phenotyping of diverse syngeneic murine brain tumors identifies immunologically distinct types10.1038/s41467-020-17704-52041-1723https://doaj.org/article/72c638431fd645f4b067eec34075de392020-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17704-5https://doaj.org/toc/2041-1723Syngeneic mouse models for glioblastoma (GBM) cannot fully recapitulate clinical findings and response to therapy in patients. Here the authors perform a comprehensive immune profiling of different syngeneic GBM tumour models and compare it with the immune landscape of GBM patients to identify similarities and potential confounding differences.Jasneet Kaur KhalsaNina ChengJoshua KeeganAmeen ChaudryJoseph DriverWenya Linda BiJames LedererKhalid ShahNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jasneet Kaur Khalsa Nina Cheng Joshua Keegan Ameen Chaudry Joseph Driver Wenya Linda Bi James Lederer Khalid Shah Immune phenotyping of diverse syngeneic murine brain tumors identifies immunologically distinct types
description	Syngeneic mouse models for glioblastoma (GBM) cannot fully recapitulate clinical findings and response to therapy in patients. Here the authors perform a comprehensive immune profiling of different syngeneic GBM tumour models and compare it with the immune landscape of GBM patients to identify similarities and potential confounding differences.
format	article
author	Jasneet Kaur Khalsa Nina Cheng Joshua Keegan Ameen Chaudry Joseph Driver Wenya Linda Bi James Lederer Khalid Shah
author_facet	Jasneet Kaur Khalsa Nina Cheng Joshua Keegan Ameen Chaudry Joseph Driver Wenya Linda Bi James Lederer Khalid Shah
author_sort	Jasneet Kaur Khalsa
title	Immune phenotyping of diverse syngeneic murine brain tumors identifies immunologically distinct types
title_short	Immune phenotyping of diverse syngeneic murine brain tumors identifies immunologically distinct types
title_full	Immune phenotyping of diverse syngeneic murine brain tumors identifies immunologically distinct types
title_fullStr	Immune phenotyping of diverse syngeneic murine brain tumors identifies immunologically distinct types
title_full_unstemmed	Immune phenotyping of diverse syngeneic murine brain tumors identifies immunologically distinct types
title_sort	immune phenotyping of diverse syngeneic murine brain tumors identifies immunologically distinct types
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/72c638431fd645f4b067eec34075de39
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Immune phenotyping of diverse syngeneic murine brain tumors identifies immunologically distinct types

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