Ring-opening functionalizations of unstrained cyclic amines enabled by difluorocarbene transfer

Cyclic amines are commonly present in natural products and synthetic compounds, but methods for their skeletal diversification are limited. Here, the authors report a strategy for selective ring-opening functionalization of unstrained cyclic amines to pluripotent products that can be further diversi...

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Autores principales:	Youyoung Kim, Joon Heo, Dongwook Kim, Sukbok Chang, Sangwon Seo
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/72ca16811b72489c85e34dc25604f0f7
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spelling	oai:doaj.org-article:72ca16811b72489c85e34dc25604f0f72021-12-02T15:15:06ZRing-opening functionalizations of unstrained cyclic amines enabled by difluorocarbene transfer10.1038/s41467-020-18557-82041-1723https://doaj.org/article/72ca16811b72489c85e34dc25604f0f72020-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18557-8https://doaj.org/toc/2041-1723Cyclic amines are commonly present in natural products and synthetic compounds, but methods for their skeletal diversification are limited. Here, the authors report a strategy for selective ring-opening functionalization of unstrained cyclic amines to pluripotent products that can be further diversified.Youyoung KimJoon HeoDongwook KimSukbok ChangSangwon SeoNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Youyoung Kim Joon Heo Dongwook Kim Sukbok Chang Sangwon Seo Ring-opening functionalizations of unstrained cyclic amines enabled by difluorocarbene transfer
description	Cyclic amines are commonly present in natural products and synthetic compounds, but methods for their skeletal diversification are limited. Here, the authors report a strategy for selective ring-opening functionalization of unstrained cyclic amines to pluripotent products that can be further diversified.
format	article
author	Youyoung Kim Joon Heo Dongwook Kim Sukbok Chang Sangwon Seo
author_facet	Youyoung Kim Joon Heo Dongwook Kim Sukbok Chang Sangwon Seo
author_sort	Youyoung Kim
title	Ring-opening functionalizations of unstrained cyclic amines enabled by difluorocarbene transfer
title_short	Ring-opening functionalizations of unstrained cyclic amines enabled by difluorocarbene transfer
title_full	Ring-opening functionalizations of unstrained cyclic amines enabled by difluorocarbene transfer
title_fullStr	Ring-opening functionalizations of unstrained cyclic amines enabled by difluorocarbene transfer
title_full_unstemmed	Ring-opening functionalizations of unstrained cyclic amines enabled by difluorocarbene transfer
title_sort	ring-opening functionalizations of unstrained cyclic amines enabled by difluorocarbene transfer
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/72ca16811b72489c85e34dc25604f0f7
work_keys_str_mv	AT youyoungkim ringopeningfunctionalizationsofunstrainedcyclicaminesenabledbydifluorocarbenetransfer AT joonheo ringopeningfunctionalizationsofunstrainedcyclicaminesenabledbydifluorocarbenetransfer AT dongwookkim ringopeningfunctionalizationsofunstrainedcyclicaminesenabledbydifluorocarbenetransfer AT sukbokchang ringopeningfunctionalizationsofunstrainedcyclicaminesenabledbydifluorocarbenetransfer AT sangwonseo ringopeningfunctionalizationsofunstrainedcyclicaminesenabledbydifluorocarbenetransfer
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Ring-opening functionalizations of unstrained cyclic amines enabled by difluorocarbene transfer

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