miRNA activity inferred from single cell mRNA expression

Abstract High throughput single-cell RNA sequencing (scRNAseq) can provide mRNA expression profiles for thousands of cells. However, miRNAs cannot currently be studied at the same scale. By exploiting that miRNAs bind well-defined sequence motifs and typically down-regulate target genes, we show tha...

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Autores principales: Morten Muhlig Nielsen, Jakob Skou Pedersen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/72cae6fbba4641afbfee8eb283e5e781
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