miRNA activity inferred from single cell mRNA expression
Abstract High throughput single-cell RNA sequencing (scRNAseq) can provide mRNA expression profiles for thousands of cells. However, miRNAs cannot currently be studied at the same scale. By exploiting that miRNAs bind well-defined sequence motifs and typically down-regulate target genes, we show tha...
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Autores principales: | Morten Muhlig Nielsen, Jakob Skou Pedersen |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/72cae6fbba4641afbfee8eb283e5e781 |
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