A family of Type VI secretion system effector proteins that form ion-selective pores

Type VI secretion systems (T6SSs) are used by bacteria to inject toxic effector proteins into neighbouring cells. Here, Mariano et al. show that an antibacterial effector from Serratia marcescens forms cation-selective pores that lead to inner-membrane depolarisation and increased outer-membrane per...

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Autores principales:	Giuseppina Mariano, Katharina Trunk, David J. Williams, Laura Monlezun, Henrik Strahl, Samantha J. Pitt, Sarah J. Coulthurst
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/72ce16c073a641019194e2b3caf69665
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spelling	oai:doaj.org-article:72ce16c073a641019194e2b3caf696652021-12-02T16:57:53ZA family of Type VI secretion system effector proteins that form ion-selective pores10.1038/s41467-019-13439-02041-1723https://doaj.org/article/72ce16c073a641019194e2b3caf696652019-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13439-0https://doaj.org/toc/2041-1723Type VI secretion systems (T6SSs) are used by bacteria to inject toxic effector proteins into neighbouring cells. Here, Mariano et al. show that an antibacterial effector from Serratia marcescens forms cation-selective pores that lead to inner-membrane depolarisation and increased outer-membrane permeability.Giuseppina MarianoKatharina TrunkDavid J. WilliamsLaura MonlezunHenrik StrahlSamantha J. PittSarah J. CoulthurstNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Giuseppina Mariano Katharina Trunk David J. Williams Laura Monlezun Henrik Strahl Samantha J. Pitt Sarah J. Coulthurst A family of Type VI secretion system effector proteins that form ion-selective pores
description	Type VI secretion systems (T6SSs) are used by bacteria to inject toxic effector proteins into neighbouring cells. Here, Mariano et al. show that an antibacterial effector from Serratia marcescens forms cation-selective pores that lead to inner-membrane depolarisation and increased outer-membrane permeability.
format	article
author	Giuseppina Mariano Katharina Trunk David J. Williams Laura Monlezun Henrik Strahl Samantha J. Pitt Sarah J. Coulthurst
author_facet	Giuseppina Mariano Katharina Trunk David J. Williams Laura Monlezun Henrik Strahl Samantha J. Pitt Sarah J. Coulthurst
author_sort	Giuseppina Mariano
title	A family of Type VI secretion system effector proteins that form ion-selective pores
title_short	A family of Type VI secretion system effector proteins that form ion-selective pores
title_full	A family of Type VI secretion system effector proteins that form ion-selective pores
title_fullStr	A family of Type VI secretion system effector proteins that form ion-selective pores
title_full_unstemmed	A family of Type VI secretion system effector proteins that form ion-selective pores
title_sort	family of type vi secretion system effector proteins that form ion-selective pores
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/72ce16c073a641019194e2b3caf69665
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A family of Type VI secretion system effector proteins that form ion-selective pores

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