High-speed volumetric two-photon fluorescence imaging of neurovascular dynamics

Monitoring hemodynamics in the brain is important in understanding medical imaging data and mechanisms of disease. Here the authors use high-throughput two-photon microscopy with an axially-extended Bessel focus to measure vessel size and blood flow down to capillary scale in the awake mouse brain.

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Autores principales:	Jiang Lan Fan, Jose A. Rivera, Wei Sun, John Peterson, Henry Haeberle, Sam Rubin, Na Ji
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/72d5129c61b241bdb21d6702666d2a38
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spelling	oai:doaj.org-article:72d5129c61b241bdb21d6702666d2a382021-12-02T16:56:51ZHigh-speed volumetric two-photon fluorescence imaging of neurovascular dynamics10.1038/s41467-020-19851-12041-1723https://doaj.org/article/72d5129c61b241bdb21d6702666d2a382020-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19851-1https://doaj.org/toc/2041-1723Monitoring hemodynamics in the brain is important in understanding medical imaging data and mechanisms of disease. Here the authors use high-throughput two-photon microscopy with an axially-extended Bessel focus to measure vessel size and blood flow down to capillary scale in the awake mouse brain.Jiang Lan FanJose A. RiveraWei SunJohn PetersonHenry HaeberleSam RubinNa JiNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jiang Lan Fan Jose A. Rivera Wei Sun John Peterson Henry Haeberle Sam Rubin Na Ji High-speed volumetric two-photon fluorescence imaging of neurovascular dynamics
description	Monitoring hemodynamics in the brain is important in understanding medical imaging data and mechanisms of disease. Here the authors use high-throughput two-photon microscopy with an axially-extended Bessel focus to measure vessel size and blood flow down to capillary scale in the awake mouse brain.
format	article
author	Jiang Lan Fan Jose A. Rivera Wei Sun John Peterson Henry Haeberle Sam Rubin Na Ji
author_facet	Jiang Lan Fan Jose A. Rivera Wei Sun John Peterson Henry Haeberle Sam Rubin Na Ji
author_sort	Jiang Lan Fan
title	High-speed volumetric two-photon fluorescence imaging of neurovascular dynamics
title_short	High-speed volumetric two-photon fluorescence imaging of neurovascular dynamics
title_full	High-speed volumetric two-photon fluorescence imaging of neurovascular dynamics
title_fullStr	High-speed volumetric two-photon fluorescence imaging of neurovascular dynamics
title_full_unstemmed	High-speed volumetric two-photon fluorescence imaging of neurovascular dynamics
title_sort	high-speed volumetric two-photon fluorescence imaging of neurovascular dynamics
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/72d5129c61b241bdb21d6702666d2a38
work_keys_str_mv	AT jianglanfan highspeedvolumetrictwophotonfluorescenceimagingofneurovasculardynamics AT josearivera highspeedvolumetrictwophotonfluorescenceimagingofneurovasculardynamics AT weisun highspeedvolumetrictwophotonfluorescenceimagingofneurovasculardynamics AT johnpeterson highspeedvolumetrictwophotonfluorescenceimagingofneurovasculardynamics AT henryhaeberle highspeedvolumetrictwophotonfluorescenceimagingofneurovasculardynamics AT samrubin highspeedvolumetrictwophotonfluorescenceimagingofneurovasculardynamics AT naji highspeedvolumetrictwophotonfluorescenceimagingofneurovasculardynamics
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High-speed volumetric two-photon fluorescence imaging of neurovascular dynamics

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