Vaccine Protection against Multidrug-Resistant <named-content content-type="genus-species">Klebsiella pneumoniae</named-content> in a Nonhuman Primate Model of Severe Lower Respiratory Tract Infection

Vaccine Protection against Multidrug-Resistant <named-content content-type="genus-species">Klebsiella pneumoniae</named-content> in a Nonhuman Primate Model of Severe Lower Respiratory Tract Infection

ABSTRACT Klebsiella pneumoniae is a human gut communal organism and notorious opportunistic pathogen. The relative high burden of asymptomatic colonization by K. pneumoniae is often compounded by multidrug resistance—a potential problem for individuals with significant comorbidities or other risk fa...

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Autores principales: Natalia Malachowa, Scott D. Kobayashi, Adeline R. Porter, Brett Freedman, Patrick W. Hanley, Jamie Lovaglio, Greg A. Saturday, Donald J. Gardner, Dana P. Scott, Amanda Griffin, Kathleen Cordova, Dan Long, Rebecca Rosenke, Daniel E. Sturdevant, Daniel Bruno, Craig Martens, Barry N. Kreiswirth, Frank R. DeLeo
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2019
Materias:
antibiotic resistance
capsule polysaccharide
bactericidal activity
nonhuman primate
pneumonia
vaccine
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/72d9814a0b744c26aa2313fd1a806127
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