Development and psychometric testing of a breast cancer patient-profiling questionnaire

Alessandra Gorini,1,2 Ketti Mazzocco,1,2 Sara Gandini,2 Elisabetta Munzone,2 Gordon McVie,2 Gabriella Pravettoni1,2 1Department of Health Science, University of Milan, Milan, Italy; 2European Institute of Oncology, Milan, Italy Introduction: The advent of “personalized medicine”...

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Autores principales:	Gorini A, Mazzocco K, Gandini S, Munzone E, McVie G, Pravettoni G
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2015
Materias:	Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Acceso en línea:	https://doaj.org/article/72ee9e56e6874d9d8a837d6051a7102b
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spelling	oai:doaj.org-article:72ee9e56e6874d9d8a837d6051a7102b2021-12-02T05:32:56ZDevelopment and psychometric testing of a breast cancer patient-profiling questionnaire1179-1314https://doaj.org/article/72ee9e56e6874d9d8a837d6051a7102b2015-06-01T00:00:00Zhttp://www.dovepress.com/development-and-psychometric-testing-of-a-breast-cancer-patient-profil-peer-reviewed-article-BCTThttps://doaj.org/toc/1179-1314Alessandra Gorini,1,2 Ketti Mazzocco,1,2 Sara Gandini,2 Elisabetta Munzone,2 Gordon McVie,2 Gabriella Pravettoni1,2 1Department of Health Science, University of Milan, Milan, Italy; 2European Institute of Oncology, Milan, Italy Introduction: The advent of “personalized medicine” has been driven by technological advances in genomics. Concentration at the subcellular level of a patient's cancer cells has meant inevitably that the “person” has been overlooked. For this reason, we think there is an urgent need to develop a truly personalized approach focusing on each patient as an individual, assessing his/her unique mental dimensions and tailoring interventions to his/her individual needs and preferences. The aim of this study was to develop and test the psychometric properties of the ALGA-Breast Cancer (ALGA-BC), a new multidimensional questionnaire that assesses the breast cancer patient's physical and mental characteristics in order to provide physicians, prior to the consultation, with a patient's profile that is supposed to facilitate subsequent communication, interaction, and information delivery between the doctor and the patient. Methods: The specific validation processes used were: content and face validity, construct validity using factor analysis, reliability and internal consistency using test–retest reliability, and Cronbach's alpha correlation coefficient. The exploratory analysis included 100 primary breast cancer patients and 730 healthy subjects. Results: The exploratory factor analysis revealed eight key factors: global self-rated health, perceived physical health, anxiety, self-efficacy, cognitive closure, memory, body image, and sexual life. Test–retest reliability and internal consistency were good. Comparing patients with a sample of healthy subjects, we also observed a general ability of the ALGA-BC questionnaire to discriminate between the two. Conclusion: The ALGA-BC questionnaire with 29 items is a valid instrument with which to obtain a patient’s profile that is supposed to help physicians achieve meaningful personalized care which supplements biological and genetic analyses. Keywords: personalized medicine, patient–physician communication, questionnaire validation, patient preferencesGorini AMazzocco KGandini SMunzone EMcVie GPravettoni GDove Medical PressarticleNeoplasms. Tumors. Oncology. Including cancer and carcinogensRC254-282ENBreast Cancer: Targets and Therapy, Vol 2015, Iss default, Pp 133-146 (2015)
institution	DOAJ
collection	DOAJ
language	EN
topic	Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
spellingShingle	Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 Gorini A Mazzocco K Gandini S Munzone E McVie G Pravettoni G Development and psychometric testing of a breast cancer patient-profiling questionnaire
description	Alessandra Gorini,1,2 Ketti Mazzocco,1,2 Sara Gandini,2 Elisabetta Munzone,2 Gordon McVie,2 Gabriella Pravettoni1,2 1Department of Health Science, University of Milan, Milan, Italy; 2European Institute of Oncology, Milan, Italy Introduction: The advent of “personalized medicine” has been driven by technological advances in genomics. Concentration at the subcellular level of a patient's cancer cells has meant inevitably that the “person” has been overlooked. For this reason, we think there is an urgent need to develop a truly personalized approach focusing on each patient as an individual, assessing his/her unique mental dimensions and tailoring interventions to his/her individual needs and preferences. The aim of this study was to develop and test the psychometric properties of the ALGA-Breast Cancer (ALGA-BC), a new multidimensional questionnaire that assesses the breast cancer patient's physical and mental characteristics in order to provide physicians, prior to the consultation, with a patient's profile that is supposed to facilitate subsequent communication, interaction, and information delivery between the doctor and the patient. Methods: The specific validation processes used were: content and face validity, construct validity using factor analysis, reliability and internal consistency using test–retest reliability, and Cronbach's alpha correlation coefficient. The exploratory analysis included 100 primary breast cancer patients and 730 healthy subjects. Results: The exploratory factor analysis revealed eight key factors: global self-rated health, perceived physical health, anxiety, self-efficacy, cognitive closure, memory, body image, and sexual life. Test–retest reliability and internal consistency were good. Comparing patients with a sample of healthy subjects, we also observed a general ability of the ALGA-BC questionnaire to discriminate between the two. Conclusion: The ALGA-BC questionnaire with 29 items is a valid instrument with which to obtain a patient’s profile that is supposed to help physicians achieve meaningful personalized care which supplements biological and genetic analyses. Keywords: personalized medicine, patient–physician communication, questionnaire validation, patient preferences
format	article
author	Gorini A Mazzocco K Gandini S Munzone E McVie G Pravettoni G
author_facet	Gorini A Mazzocco K Gandini S Munzone E McVie G Pravettoni G
author_sort	Gorini A
title	Development and psychometric testing of a breast cancer patient-profiling questionnaire
title_short	Development and psychometric testing of a breast cancer patient-profiling questionnaire
title_full	Development and psychometric testing of a breast cancer patient-profiling questionnaire
title_fullStr	Development and psychometric testing of a breast cancer patient-profiling questionnaire
title_full_unstemmed	Development and psychometric testing of a breast cancer patient-profiling questionnaire
title_sort	development and psychometric testing of a breast cancer patient-profiling questionnaire
publisher	Dove Medical Press
publishDate	2015
url	https://doaj.org/article/72ee9e56e6874d9d8a837d6051a7102b
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Development and psychometric testing of a breast cancer patient-profiling questionnaire

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