Cysteine-mediated decyanation of vitamin B12 by the predicted membrane transporter BtuM
Uptake of vitamin B12 is essential for many prokaryotes, but in most cases the membrane proteins involved are yet to be identified. Here, the authors use X-ray crystallography and spectroscopy to characterize BtuM, a predicted bacterial substrate-modifying vitamin B12 transporter.
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Nature Portfolio
2018
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oai:doaj.org-article:72fc0697a8c449729feb9bbe1e3643d92021-12-02T14:39:08ZCysteine-mediated decyanation of vitamin B12 by the predicted membrane transporter BtuM10.1038/s41467-018-05441-92041-1723https://doaj.org/article/72fc0697a8c449729feb9bbe1e3643d92018-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05441-9https://doaj.org/toc/2041-1723Uptake of vitamin B12 is essential for many prokaryotes, but in most cases the membrane proteins involved are yet to be identified. Here, the authors use X-ray crystallography and spectroscopy to characterize BtuM, a predicted bacterial substrate-modifying vitamin B12 transporter.S. RempelE. ColucciJ. W. de GierA. GuskovD. J. SlotboomNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-8 (2018) |
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Science Q S. Rempel E. Colucci J. W. de Gier A. Guskov D. J. Slotboom Cysteine-mediated decyanation of vitamin B12 by the predicted membrane transporter BtuM |
description |
Uptake of vitamin B12 is essential for many prokaryotes, but in most cases the membrane proteins involved are yet to be identified. Here, the authors use X-ray crystallography and spectroscopy to characterize BtuM, a predicted bacterial substrate-modifying vitamin B12 transporter. |
format |
article |
author |
S. Rempel E. Colucci J. W. de Gier A. Guskov D. J. Slotboom |
author_facet |
S. Rempel E. Colucci J. W. de Gier A. Guskov D. J. Slotboom |
author_sort |
S. Rempel |
title |
Cysteine-mediated decyanation of vitamin B12 by the predicted membrane transporter BtuM |
title_short |
Cysteine-mediated decyanation of vitamin B12 by the predicted membrane transporter BtuM |
title_full |
Cysteine-mediated decyanation of vitamin B12 by the predicted membrane transporter BtuM |
title_fullStr |
Cysteine-mediated decyanation of vitamin B12 by the predicted membrane transporter BtuM |
title_full_unstemmed |
Cysteine-mediated decyanation of vitamin B12 by the predicted membrane transporter BtuM |
title_sort |
cysteine-mediated decyanation of vitamin b12 by the predicted membrane transporter btum |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/72fc0697a8c449729feb9bbe1e3643d9 |
work_keys_str_mv |
AT srempel cysteinemediateddecyanationofvitaminb12bythepredictedmembranetransporterbtum AT ecolucci cysteinemediateddecyanationofvitaminb12bythepredictedmembranetransporterbtum AT jwdegier cysteinemediateddecyanationofvitaminb12bythepredictedmembranetransporterbtum AT aguskov cysteinemediateddecyanationofvitaminb12bythepredictedmembranetransporterbtum AT djslotboom cysteinemediateddecyanationofvitaminb12bythepredictedmembranetransporterbtum |
_version_ |
1718390720323125248 |