Cysteine-mediated decyanation of vitamin B12 by the predicted membrane transporter BtuM

Uptake of vitamin B12 is essential for many prokaryotes, but in most cases the membrane proteins involved are yet to be identified. Here, the authors use X-ray crystallography and spectroscopy to characterize BtuM, a predicted bacterial substrate-modifying vitamin B12 transporter.

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Autores principales: S. Rempel, E. Colucci, J. W. de Gier, A. Guskov, D. J. Slotboom
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/72fc0697a8c449729feb9bbe1e3643d9
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spelling oai:doaj.org-article:72fc0697a8c449729feb9bbe1e3643d92021-12-02T14:39:08ZCysteine-mediated decyanation of vitamin B12 by the predicted membrane transporter BtuM10.1038/s41467-018-05441-92041-1723https://doaj.org/article/72fc0697a8c449729feb9bbe1e3643d92018-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05441-9https://doaj.org/toc/2041-1723Uptake of vitamin B12 is essential for many prokaryotes, but in most cases the membrane proteins involved are yet to be identified. Here, the authors use X-ray crystallography and spectroscopy to characterize BtuM, a predicted bacterial substrate-modifying vitamin B12 transporter.S. RempelE. ColucciJ. W. de GierA. GuskovD. J. SlotboomNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-8 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
S. Rempel
E. Colucci
J. W. de Gier
A. Guskov
D. J. Slotboom
Cysteine-mediated decyanation of vitamin B12 by the predicted membrane transporter BtuM
description Uptake of vitamin B12 is essential for many prokaryotes, but in most cases the membrane proteins involved are yet to be identified. Here, the authors use X-ray crystallography and spectroscopy to characterize BtuM, a predicted bacterial substrate-modifying vitamin B12 transporter.
format article
author S. Rempel
E. Colucci
J. W. de Gier
A. Guskov
D. J. Slotboom
author_facet S. Rempel
E. Colucci
J. W. de Gier
A. Guskov
D. J. Slotboom
author_sort S. Rempel
title Cysteine-mediated decyanation of vitamin B12 by the predicted membrane transporter BtuM
title_short Cysteine-mediated decyanation of vitamin B12 by the predicted membrane transporter BtuM
title_full Cysteine-mediated decyanation of vitamin B12 by the predicted membrane transporter BtuM
title_fullStr Cysteine-mediated decyanation of vitamin B12 by the predicted membrane transporter BtuM
title_full_unstemmed Cysteine-mediated decyanation of vitamin B12 by the predicted membrane transporter BtuM
title_sort cysteine-mediated decyanation of vitamin b12 by the predicted membrane transporter btum
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/72fc0697a8c449729feb9bbe1e3643d9
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