Epigenetic mechanisms in breast cancer therapy and resistance

Endocrine therapy has been the mainstay for hormone responsive breast cancer treatment. Here, Garcia-Martinez and colleagues discuss epigenetic mechanisms regulating ER + breast cancer and endocrine therapy resistance, and highlight approaches to rewire the cancer epigenome to improve targeted thera...

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Autores principales:	Liliana Garcia-Martinez, Yusheng Zhang, Yuichiro Nakata, Ho Lam Chan, Lluis Morey
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/72fca6909b8442fd93cfeeb4fe4cabd1
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spelling	oai:doaj.org-article:72fca6909b8442fd93cfeeb4fe4cabd12021-12-02T11:39:32ZEpigenetic mechanisms in breast cancer therapy and resistance10.1038/s41467-021-22024-32041-1723https://doaj.org/article/72fca6909b8442fd93cfeeb4fe4cabd12021-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22024-3https://doaj.org/toc/2041-1723Endocrine therapy has been the mainstay for hormone responsive breast cancer treatment. Here, Garcia-Martinez and colleagues discuss epigenetic mechanisms regulating ER + breast cancer and endocrine therapy resistance, and highlight approaches to rewire the cancer epigenome to improve targeted therapies for this cancer.Liliana Garcia-MartinezYusheng ZhangYuichiro NakataHo Lam ChanLluis MoreyNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Liliana Garcia-Martinez Yusheng Zhang Yuichiro Nakata Ho Lam Chan Lluis Morey Epigenetic mechanisms in breast cancer therapy and resistance
description	Endocrine therapy has been the mainstay for hormone responsive breast cancer treatment. Here, Garcia-Martinez and colleagues discuss epigenetic mechanisms regulating ER + breast cancer and endocrine therapy resistance, and highlight approaches to rewire the cancer epigenome to improve targeted therapies for this cancer.
format	article
author	Liliana Garcia-Martinez Yusheng Zhang Yuichiro Nakata Ho Lam Chan Lluis Morey
author_facet	Liliana Garcia-Martinez Yusheng Zhang Yuichiro Nakata Ho Lam Chan Lluis Morey
author_sort	Liliana Garcia-Martinez
title	Epigenetic mechanisms in breast cancer therapy and resistance
title_short	Epigenetic mechanisms in breast cancer therapy and resistance
title_full	Epigenetic mechanisms in breast cancer therapy and resistance
title_fullStr	Epigenetic mechanisms in breast cancer therapy and resistance
title_full_unstemmed	Epigenetic mechanisms in breast cancer therapy and resistance
title_sort	epigenetic mechanisms in breast cancer therapy and resistance
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/72fca6909b8442fd93cfeeb4fe4cabd1
work_keys_str_mv	AT lilianagarciamartinez epigeneticmechanismsinbreastcancertherapyandresistance AT yushengzhang epigeneticmechanismsinbreastcancertherapyandresistance AT yuichironakata epigeneticmechanismsinbreastcancertherapyandresistance AT holamchan epigeneticmechanismsinbreastcancertherapyandresistance AT lluismorey epigeneticmechanismsinbreastcancertherapyandresistance
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Epigenetic mechanisms in breast cancer therapy and resistance

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