A small secreted protein triggers a TLR2/4-dependent inflammatory response during invasive Candida albicans infection

The interplay between fungal pathogens and the innate immune system remains incompletely understood. Here, Wang et al. show that a small protein secreted by Candida albicans induces a TLR2- and TLR4-mediated inflammatory response in a mouse infection model.

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Detalles Bibliográficos
Autores principales: Wenjuan Wang, Zihou Deng, Hongyu Wu, Qun Zhao, Tiantian Li, Wencheng Zhu, Xiongjun Wang, Longhai Tang, Chengshu Wang, Shu-Zhong Cui, Hui Xiao, Jiangye Chen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/730ad81173b04795be2435941fb6a493
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Sumario:The interplay between fungal pathogens and the innate immune system remains incompletely understood. Here, Wang et al. show that a small protein secreted by Candida albicans induces a TLR2- and TLR4-mediated inflammatory response in a mouse infection model.