A small secreted protein triggers a TLR2/4-dependent inflammatory response during invasive Candida albicans infection

The interplay between fungal pathogens and the innate immune system remains incompletely understood. Here, Wang et al. show that a small protein secreted by Candida albicans induces a TLR2- and TLR4-mediated inflammatory response in a mouse infection model.

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Autores principales:	Wenjuan Wang, Zihou Deng, Hongyu Wu, Qun Zhao, Tiantian Li, Wencheng Zhu, Xiongjun Wang, Longhai Tang, Chengshu Wang, Shu-Zhong Cui, Hui Xiao, Jiangye Chen
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/730ad81173b04795be2435941fb6a493
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spelling	oai:doaj.org-article:730ad81173b04795be2435941fb6a4932021-12-02T15:35:38ZA small secreted protein triggers a TLR2/4-dependent inflammatory response during invasive Candida albicans infection10.1038/s41467-019-08950-32041-1723https://doaj.org/article/730ad81173b04795be2435941fb6a4932019-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-08950-3https://doaj.org/toc/2041-1723The interplay between fungal pathogens and the innate immune system remains incompletely understood. Here, Wang et al. show that a small protein secreted by Candida albicans induces a TLR2- and TLR4-mediated inflammatory response in a mouse infection model.Wenjuan WangZihou DengHongyu WuQun ZhaoTiantian LiWencheng ZhuXiongjun WangLonghai TangChengshu WangShu-Zhong CuiHui XiaoJiangye ChenNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Wenjuan Wang Zihou Deng Hongyu Wu Qun Zhao Tiantian Li Wencheng Zhu Xiongjun Wang Longhai Tang Chengshu Wang Shu-Zhong Cui Hui Xiao Jiangye Chen A small secreted protein triggers a TLR2/4-dependent inflammatory response during invasive Candida albicans infection
description	The interplay between fungal pathogens and the innate immune system remains incompletely understood. Here, Wang et al. show that a small protein secreted by Candida albicans induces a TLR2- and TLR4-mediated inflammatory response in a mouse infection model.
format	article
author	Wenjuan Wang Zihou Deng Hongyu Wu Qun Zhao Tiantian Li Wencheng Zhu Xiongjun Wang Longhai Tang Chengshu Wang Shu-Zhong Cui Hui Xiao Jiangye Chen
author_facet	Wenjuan Wang Zihou Deng Hongyu Wu Qun Zhao Tiantian Li Wencheng Zhu Xiongjun Wang Longhai Tang Chengshu Wang Shu-Zhong Cui Hui Xiao Jiangye Chen
author_sort	Wenjuan Wang
title	A small secreted protein triggers a TLR2/4-dependent inflammatory response during invasive Candida albicans infection
title_short	A small secreted protein triggers a TLR2/4-dependent inflammatory response during invasive Candida albicans infection
title_full	A small secreted protein triggers a TLR2/4-dependent inflammatory response during invasive Candida albicans infection
title_fullStr	A small secreted protein triggers a TLR2/4-dependent inflammatory response during invasive Candida albicans infection
title_full_unstemmed	A small secreted protein triggers a TLR2/4-dependent inflammatory response during invasive Candida albicans infection
title_sort	small secreted protein triggers a tlr2/4-dependent inflammatory response during invasive candida albicans infection
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/730ad81173b04795be2435941fb6a493
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A small secreted protein triggers a TLR2/4-dependent inflammatory response during invasive Candida albicans infection

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