Factors associated with antiretroviral therapy adherence among people living with HIV in Haiti: a cross-sectional study

Abstract Background Socioeconomic, demographic and clinical factors can affect adherence to treatment among people living with HIV (PLH) and potentially have an impact on their prognosis and survival. The main objective of this study was to assess these factors as potential barriers to adherence amo...

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Autores principales: Ludentz Dorcélus, Joseph Bernard, Constant Georgery, Clerveau Vanessa
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Publicado: BMC 2021
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spelling oai:doaj.org-article:730bb6d9a9974c498f71337d9a6f5cb42021-11-07T12:08:15ZFactors associated with antiretroviral therapy adherence among people living with HIV in Haiti: a cross-sectional study10.1186/s12981-021-00405-41742-6405https://doaj.org/article/730bb6d9a9974c498f71337d9a6f5cb42021-11-01T00:00:00Zhttps://doi.org/10.1186/s12981-021-00405-4https://doaj.org/toc/1742-6405Abstract Background Socioeconomic, demographic and clinical factors can affect adherence to treatment among people living with HIV (PLH) and potentially have an impact on their prognosis and survival. The main objective of this study was to assess these factors as potential barriers to adherence among patients receiving care in central Haiti. Methods A cross-sectional study was conducted among PLH receiving antiretroviral therapy (ART) at the TB/HIV clinic at St. Therese Hospital in Hinche, Haiti. A total of 426 potential participants were approached during their follow-up visits from June to August 2019, of whom 411 participated in the study. After giving informed consent, study participants completed a structured interview that included the Self-Report Item Scale (SRIS), a standard measure, to assess adherence. Socio-demographic, economic and clinical factors were assessed for their association with adherence. Results The 411 participating patients represented 39% of the patient population at the TB/HIV clinic during the timeframe of the study. The mean age was 43.7 years (range: 19–80), 65.5% were female and 78.1% had only achieved a primary level of schooling. Nearly 78% had received ART for less than 10 years, 3.41% reported having poor adherence and 28% less than excellent adherence. Factors related to poor adherence in bivariate analysis were age less than 40 years (OR: 6.32, 95% CI 2.04–10.58, p < 0.01) and inability to meet basic needs (OR: 2.70, 95% CI 1.04–7.0, p = 0.03). Conclusions To improve medication adherence, the hospital should strengthen patient counselling of younger recipients of ART and provide financial assistance and other social service interventions. Studies should be implemented in other HIV management centers in Haiti and similar contexts to examine barriers to ART adherence with the goal of improving prognosis and survival in the long-term among PLH in resource-limited setting.Ludentz DorcélusJoseph BernardConstant GeorgeryClerveau VanessaBMCarticleAdherence HIVHaitiAntiretroviral therapyImmunologic diseases. AllergyRC581-607ENAIDS Research and Therapy, Vol 18, Iss 1, Pp 1-9 (2021)
institution DOAJ
collection DOAJ
language EN
topic Adherence HIV
Haiti
Antiretroviral therapy
Immunologic diseases. Allergy
RC581-607
spellingShingle Adherence HIV
Haiti
Antiretroviral therapy
Immunologic diseases. Allergy
RC581-607
Ludentz Dorcélus
Joseph Bernard
Constant Georgery
Clerveau Vanessa
Factors associated with antiretroviral therapy adherence among people living with HIV in Haiti: a cross-sectional study
description Abstract Background Socioeconomic, demographic and clinical factors can affect adherence to treatment among people living with HIV (PLH) and potentially have an impact on their prognosis and survival. The main objective of this study was to assess these factors as potential barriers to adherence among patients receiving care in central Haiti. Methods A cross-sectional study was conducted among PLH receiving antiretroviral therapy (ART) at the TB/HIV clinic at St. Therese Hospital in Hinche, Haiti. A total of 426 potential participants were approached during their follow-up visits from June to August 2019, of whom 411 participated in the study. After giving informed consent, study participants completed a structured interview that included the Self-Report Item Scale (SRIS), a standard measure, to assess adherence. Socio-demographic, economic and clinical factors were assessed for their association with adherence. Results The 411 participating patients represented 39% of the patient population at the TB/HIV clinic during the timeframe of the study. The mean age was 43.7 years (range: 19–80), 65.5% were female and 78.1% had only achieved a primary level of schooling. Nearly 78% had received ART for less than 10 years, 3.41% reported having poor adherence and 28% less than excellent adherence. Factors related to poor adherence in bivariate analysis were age less than 40 years (OR: 6.32, 95% CI 2.04–10.58, p < 0.01) and inability to meet basic needs (OR: 2.70, 95% CI 1.04–7.0, p = 0.03). Conclusions To improve medication adherence, the hospital should strengthen patient counselling of younger recipients of ART and provide financial assistance and other social service interventions. Studies should be implemented in other HIV management centers in Haiti and similar contexts to examine barriers to ART adherence with the goal of improving prognosis and survival in the long-term among PLH in resource-limited setting.
format article
author Ludentz Dorcélus
Joseph Bernard
Constant Georgery
Clerveau Vanessa
author_facet Ludentz Dorcélus
Joseph Bernard
Constant Georgery
Clerveau Vanessa
author_sort Ludentz Dorcélus
title Factors associated with antiretroviral therapy adherence among people living with HIV in Haiti: a cross-sectional study
title_short Factors associated with antiretroviral therapy adherence among people living with HIV in Haiti: a cross-sectional study
title_full Factors associated with antiretroviral therapy adherence among people living with HIV in Haiti: a cross-sectional study
title_fullStr Factors associated with antiretroviral therapy adherence among people living with HIV in Haiti: a cross-sectional study
title_full_unstemmed Factors associated with antiretroviral therapy adherence among people living with HIV in Haiti: a cross-sectional study
title_sort factors associated with antiretroviral therapy adherence among people living with hiv in haiti: a cross-sectional study
publisher BMC
publishDate 2021
url https://doaj.org/article/730bb6d9a9974c498f71337d9a6f5cb4
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AT josephbernard factorsassociatedwithantiretroviraltherapyadherenceamongpeoplelivingwithhivinhaitiacrosssectionalstudy
AT constantgeorgery factorsassociatedwithantiretroviraltherapyadherenceamongpeoplelivingwithhivinhaitiacrosssectionalstudy
AT clerveauvanessa factorsassociatedwithantiretroviraltherapyadherenceamongpeoplelivingwithhivinhaitiacrosssectionalstudy
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