Risk assessment and prognostic analysis of patients with splenic infarction in emergency department: a multicenter retrospective study

Abstract Splenic infarction is a thromboembolic disease that is frequently missed in acute settings. Previous reviews were rarely presented from a clinical perspective. We aimed to evaluate the clinical characteristics, risk factors with diagnostic value, and prognostic factors using large cohort da...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Chieh-Ching Yen, Chih-Kai Wang, Shou-Yen Chen, Shi-Ying Gao, Hsiang-Yun Lo, Chip-Jin Ng, Chung-Hsien Chaou
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/730eb82472124e6896fbc153cbb6cb5c
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:730eb82472124e6896fbc153cbb6cb5c
record_format	dspace
spelling	oai:doaj.org-article:730eb82472124e6896fbc153cbb6cb5c2021-11-08T10:55:20ZRisk assessment and prognostic analysis of patients with splenic infarction in emergency department: a multicenter retrospective study10.1038/s41598-021-00897-02045-2322https://doaj.org/article/730eb82472124e6896fbc153cbb6cb5c2021-11-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-00897-0https://doaj.org/toc/2045-2322Abstract Splenic infarction is a thromboembolic disease that is frequently missed in acute settings. Previous reviews were rarely presented from a clinical perspective. We aimed to evaluate the clinical characteristics, risk factors with diagnostic value, and prognostic factors using large cohort data and a matched case–control study method. A retrospective medical record review of six hospitals in Taiwan from January 1, 2005, to August 31, 2020, was conducted. All patients who underwent contrast CT with confirmed the diagnosis of splenic infarction were included. Their characteristics were presented and compared to a matched control group with similar presenting characteristics. Prognostic factors were also analyzed. A total of 130 cases were included, two-thirds of whom presented with abdominal pain. Atrial fibrillation was the most common associated predisposing condition, followed by hematologic disease. A higher proportion of tachycardia, positive qSOFA score, history of hypertension or atrial fibrillation, leukocytosis, and thrombocytopenia were found in splenic infarction patients compared to their counterparts. An underlying etiology of infective endocarditis was associated with a higher proportion of ICU admission. Splenic infarction patients often presented with left upper abdominal pain and tachycardia. A history of hypertension, atrial fibrillation, a laboratory result of leukocytosis or thrombocytopenia may provide a clue for clinicians to include splenic infarction in the differential list. Among the patients diagnosed with splenic infarction, those with an underlying etiology of infectious endocarditis may be prone to deterioration or ICU admission.Chieh-Ching YenChih-Kai WangShou-Yen ChenShi-Ying GaoHsiang-Yun LoChip-Jin NgChung-Hsien ChaouNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Chieh-Ching Yen Chih-Kai Wang Shou-Yen Chen Shi-Ying Gao Hsiang-Yun Lo Chip-Jin Ng Chung-Hsien Chaou Risk assessment and prognostic analysis of patients with splenic infarction in emergency department: a multicenter retrospective study
description	Abstract Splenic infarction is a thromboembolic disease that is frequently missed in acute settings. Previous reviews were rarely presented from a clinical perspective. We aimed to evaluate the clinical characteristics, risk factors with diagnostic value, and prognostic factors using large cohort data and a matched case–control study method. A retrospective medical record review of six hospitals in Taiwan from January 1, 2005, to August 31, 2020, was conducted. All patients who underwent contrast CT with confirmed the diagnosis of splenic infarction were included. Their characteristics were presented and compared to a matched control group with similar presenting characteristics. Prognostic factors were also analyzed. A total of 130 cases were included, two-thirds of whom presented with abdominal pain. Atrial fibrillation was the most common associated predisposing condition, followed by hematologic disease. A higher proportion of tachycardia, positive qSOFA score, history of hypertension or atrial fibrillation, leukocytosis, and thrombocytopenia were found in splenic infarction patients compared to their counterparts. An underlying etiology of infective endocarditis was associated with a higher proportion of ICU admission. Splenic infarction patients often presented with left upper abdominal pain and tachycardia. A history of hypertension, atrial fibrillation, a laboratory result of leukocytosis or thrombocytopenia may provide a clue for clinicians to include splenic infarction in the differential list. Among the patients diagnosed with splenic infarction, those with an underlying etiology of infectious endocarditis may be prone to deterioration or ICU admission.
format	article
author	Chieh-Ching Yen Chih-Kai Wang Shou-Yen Chen Shi-Ying Gao Hsiang-Yun Lo Chip-Jin Ng Chung-Hsien Chaou
author_facet	Chieh-Ching Yen Chih-Kai Wang Shou-Yen Chen Shi-Ying Gao Hsiang-Yun Lo Chip-Jin Ng Chung-Hsien Chaou
author_sort	Chieh-Ching Yen
title	Risk assessment and prognostic analysis of patients with splenic infarction in emergency department: a multicenter retrospective study
title_short	Risk assessment and prognostic analysis of patients with splenic infarction in emergency department: a multicenter retrospective study
title_full	Risk assessment and prognostic analysis of patients with splenic infarction in emergency department: a multicenter retrospective study
title_fullStr	Risk assessment and prognostic analysis of patients with splenic infarction in emergency department: a multicenter retrospective study
title_full_unstemmed	Risk assessment and prognostic analysis of patients with splenic infarction in emergency department: a multicenter retrospective study
title_sort	risk assessment and prognostic analysis of patients with splenic infarction in emergency department: a multicenter retrospective study
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/730eb82472124e6896fbc153cbb6cb5c
work_keys_str_mv	AT chiehchingyen riskassessmentandprognosticanalysisofpatientswithsplenicinfarctioninemergencydepartmentamulticenterretrospectivestudy AT chihkaiwang riskassessmentandprognosticanalysisofpatientswithsplenicinfarctioninemergencydepartmentamulticenterretrospectivestudy AT shouyenchen riskassessmentandprognosticanalysisofpatientswithsplenicinfarctioninemergencydepartmentamulticenterretrospectivestudy AT shiyinggao riskassessmentandprognosticanalysisofpatientswithsplenicinfarctioninemergencydepartmentamulticenterretrospectivestudy AT hsiangyunlo riskassessmentandprognosticanalysisofpatientswithsplenicinfarctioninemergencydepartmentamulticenterretrospectivestudy AT chipjinng riskassessmentandprognosticanalysisofpatientswithsplenicinfarctioninemergencydepartmentamulticenterretrospectivestudy AT chunghsienchaou riskassessmentandprognosticanalysisofpatientswithsplenicinfarctioninemergencydepartmentamulticenterretrospectivestudy
_version_	1718442537336700928

Risk assessment and prognostic analysis of patients with splenic infarction in emergency department: a multicenter retrospective study

Ejemplares similares