Prevalence of G6PD deficiency among primary school students in Amol

Background and Objective: G6PD (Glucose-6-phosphate dehydrogenase) deficiency is the most common enzyme deficiency in human beings. Using fava beans, some drugs are oxidant agents cause life-threatening hemolysis in children and other ages. The aim of this study was to determine the prevalence of G6...

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Autores principales: A Hashemi, Y ZahedPasha, M Haji Ahmadi, B Alaei
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Lenguaje:EN
FA
Publicado: Babol University of Medical Sciences 2005
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Acceso en línea:https://doaj.org/article/73138058c78948c3908a67d70d30171a
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spelling oai:doaj.org-article:73138058c78948c3908a67d70d30171a2021-11-10T09:14:24ZPrevalence of G6PD deficiency among primary school students in Amol1561-41072251-7170https://doaj.org/article/73138058c78948c3908a67d70d30171a2005-01-01T00:00:00Zhttp://jbums.org/article-1-2654-en.htmlhttps://doaj.org/toc/1561-4107https://doaj.org/toc/2251-7170Background and Objective: G6PD (Glucose-6-phosphate dehydrogenase) deficiency is the most common enzyme deficiency in human beings. Using fava beans, some drugs are oxidant agents cause life-threatening hemolysis in children and other ages. The aim of this study was to determine the prevalence of G6PD deficiency and its relation to age and family history. Methods: This cross-sectional, descriptive and analytical study was performed on 732 persons. Students aged between 7-11 years old were randomly chosen by cluster sampling method. Data were analyzed by SPSS. For comparing enzyme deficiency between 2 sexes and the effect of family history, Chi-square test was used. Findings: From 732 students, 295 were male and 437 were female. 11.2% of males and 1.4% of females were G6PD deficient that this difference was considered significant (P<0.0001). Children who have G6PD deficiency, history of G6PD deficiency among their family members was significantly more (P<0.0001). Conclusion: Due to high prevalence of G6PD deficiency as a threatening factor for public health in north of Iran, it is suggested cord blood G6PD screening be considered at birth especially in male neonates and the quality of primary health care and public information be increased by teaching.A HashemiY ZahedPashaM Haji AhmadiB AlaeiBabol University of Medical Sciencesarticleg6pdfavismscreeningsexfamily historyMedicineRMedicine (General)R5-920ENFAMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, Vol 7, Iss 1, Pp 52-56 (2005)
institution DOAJ
collection DOAJ
language EN
FA
topic g6pd
favism
screening
sex
family history
Medicine
R
Medicine (General)
R5-920
spellingShingle g6pd
favism
screening
sex
family history
Medicine
R
Medicine (General)
R5-920
A Hashemi
Y ZahedPasha
M Haji Ahmadi
B Alaei
Prevalence of G6PD deficiency among primary school students in Amol
description Background and Objective: G6PD (Glucose-6-phosphate dehydrogenase) deficiency is the most common enzyme deficiency in human beings. Using fava beans, some drugs are oxidant agents cause life-threatening hemolysis in children and other ages. The aim of this study was to determine the prevalence of G6PD deficiency and its relation to age and family history. Methods: This cross-sectional, descriptive and analytical study was performed on 732 persons. Students aged between 7-11 years old were randomly chosen by cluster sampling method. Data were analyzed by SPSS. For comparing enzyme deficiency between 2 sexes and the effect of family history, Chi-square test was used. Findings: From 732 students, 295 were male and 437 were female. 11.2% of males and 1.4% of females were G6PD deficient that this difference was considered significant (P<0.0001). Children who have G6PD deficiency, history of G6PD deficiency among their family members was significantly more (P<0.0001). Conclusion: Due to high prevalence of G6PD deficiency as a threatening factor for public health in north of Iran, it is suggested cord blood G6PD screening be considered at birth especially in male neonates and the quality of primary health care and public information be increased by teaching.
format article
author A Hashemi
Y ZahedPasha
M Haji Ahmadi
B Alaei
author_facet A Hashemi
Y ZahedPasha
M Haji Ahmadi
B Alaei
author_sort A Hashemi
title Prevalence of G6PD deficiency among primary school students in Amol
title_short Prevalence of G6PD deficiency among primary school students in Amol
title_full Prevalence of G6PD deficiency among primary school students in Amol
title_fullStr Prevalence of G6PD deficiency among primary school students in Amol
title_full_unstemmed Prevalence of G6PD deficiency among primary school students in Amol
title_sort prevalence of g6pd deficiency among primary school students in amol
publisher Babol University of Medical Sciences
publishDate 2005
url https://doaj.org/article/73138058c78948c3908a67d70d30171a
work_keys_str_mv AT ahashemi prevalenceofg6pddeficiencyamongprimaryschoolstudentsinamol
AT yzahedpasha prevalenceofg6pddeficiencyamongprimaryschoolstudentsinamol
AT mhajiahmadi prevalenceofg6pddeficiencyamongprimaryschoolstudentsinamol
AT balaei prevalenceofg6pddeficiencyamongprimaryschoolstudentsinamol
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