Plasmodium falciparum sexual differentiation in malaria patients is associated with host factors and GDV1-dependent genes

Plasmodium falciparum sexual differentiation in malaria patients is associated with host factors and GDV1-dependent genes

Here, the authors quantify early gametocyte-committed ring (gc-ring) stage Plasmodium falciparum parasites in 260 malaria patients 10 days before maturation to transmissible stage V gametocytes, and show that the ratio of circulating gc-rings is positively correlated with parasitemia and negatively...

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Auteurs principaux: Miho Usui, Surendra K. Prajapati, Ruth Ayanful-Torgby, Festus K. Acquah, Elizabeth Cudjoe, Courage Kakaney, Jones A. Amponsah, Evans K. Obboh, Deepti K. Reddy, Michelle C. Barbeau, Lacy M. Simons, Beata Czesny, Sorana Raiciulescu, Cara Olsen, Benjamin K. Abuaku, Linda E. Amoah, Kim C. Williamson
Format: article
Langue:EN
Publié: Nature Portfolio 2019
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Science
Q
Accès en ligne:https://doaj.org/article/73141292ad324d40a033d356781f23b7
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Résumé:Here, the authors quantify early gametocyte-committed ring (gc-ring) stage Plasmodium falciparum parasites in 260 malaria patients 10 days before maturation to transmissible stage V gametocytes, and show that the ratio of circulating gc-rings is positively correlated with parasitemia and negatively correlated with body temperature.

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