Plasmodium falciparum sexual differentiation in malaria patients is associated with host factors and GDV1-dependent genes

Here, the authors quantify early gametocyte-committed ring (gc-ring) stage Plasmodium falciparum parasites in 260 malaria patients 10 days before maturation to transmissible stage V gametocytes, and show that the ratio of circulating gc-rings is positively correlated with parasitemia and negatively...

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Autores principales: Miho Usui, Surendra K. Prajapati, Ruth Ayanful-Torgby, Festus K. Acquah, Elizabeth Cudjoe, Courage Kakaney, Jones A. Amponsah, Evans K. Obboh, Deepti K. Reddy, Michelle C. Barbeau, Lacy M. Simons, Beata Czesny, Sorana Raiciulescu, Cara Olsen, Benjamin K. Abuaku, Linda E. Amoah, Kim C. Williamson
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Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/73141292ad324d40a033d356781f23b7
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spelling oai:doaj.org-article:73141292ad324d40a033d356781f23b72021-12-02T15:35:09ZPlasmodium falciparum sexual differentiation in malaria patients is associated with host factors and GDV1-dependent genes10.1038/s41467-019-10172-62041-1723https://doaj.org/article/73141292ad324d40a033d356781f23b72019-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10172-6https://doaj.org/toc/2041-1723Here, the authors quantify early gametocyte-committed ring (gc-ring) stage Plasmodium falciparum parasites in 260 malaria patients 10 days before maturation to transmissible stage V gametocytes, and show that the ratio of circulating gc-rings is positively correlated with parasitemia and negatively correlated with body temperature.Miho UsuiSurendra K. PrajapatiRuth Ayanful-TorgbyFestus K. AcquahElizabeth CudjoeCourage KakaneyJones A. AmponsahEvans K. ObbohDeepti K. ReddyMichelle C. BarbeauLacy M. SimonsBeata CzesnySorana RaiciulescuCara OlsenBenjamin K. AbuakuLinda E. AmoahKim C. WilliamsonNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Miho Usui
Surendra K. Prajapati
Ruth Ayanful-Torgby
Festus K. Acquah
Elizabeth Cudjoe
Courage Kakaney
Jones A. Amponsah
Evans K. Obboh
Deepti K. Reddy
Michelle C. Barbeau
Lacy M. Simons
Beata Czesny
Sorana Raiciulescu
Cara Olsen
Benjamin K. Abuaku
Linda E. Amoah
Kim C. Williamson
Plasmodium falciparum sexual differentiation in malaria patients is associated with host factors and GDV1-dependent genes
description Here, the authors quantify early gametocyte-committed ring (gc-ring) stage Plasmodium falciparum parasites in 260 malaria patients 10 days before maturation to transmissible stage V gametocytes, and show that the ratio of circulating gc-rings is positively correlated with parasitemia and negatively correlated with body temperature.
format article
author Miho Usui
Surendra K. Prajapati
Ruth Ayanful-Torgby
Festus K. Acquah
Elizabeth Cudjoe
Courage Kakaney
Jones A. Amponsah
Evans K. Obboh
Deepti K. Reddy
Michelle C. Barbeau
Lacy M. Simons
Beata Czesny
Sorana Raiciulescu
Cara Olsen
Benjamin K. Abuaku
Linda E. Amoah
Kim C. Williamson
author_facet Miho Usui
Surendra K. Prajapati
Ruth Ayanful-Torgby
Festus K. Acquah
Elizabeth Cudjoe
Courage Kakaney
Jones A. Amponsah
Evans K. Obboh
Deepti K. Reddy
Michelle C. Barbeau
Lacy M. Simons
Beata Czesny
Sorana Raiciulescu
Cara Olsen
Benjamin K. Abuaku
Linda E. Amoah
Kim C. Williamson
author_sort Miho Usui
title Plasmodium falciparum sexual differentiation in malaria patients is associated with host factors and GDV1-dependent genes
title_short Plasmodium falciparum sexual differentiation in malaria patients is associated with host factors and GDV1-dependent genes
title_full Plasmodium falciparum sexual differentiation in malaria patients is associated with host factors and GDV1-dependent genes
title_fullStr Plasmodium falciparum sexual differentiation in malaria patients is associated with host factors and GDV1-dependent genes
title_full_unstemmed Plasmodium falciparum sexual differentiation in malaria patients is associated with host factors and GDV1-dependent genes
title_sort plasmodium falciparum sexual differentiation in malaria patients is associated with host factors and gdv1-dependent genes
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/73141292ad324d40a033d356781f23b7
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