<i>Leishmania</i> and the Model of Predominant Clonal Evolution

As it is the case for other pathogenic microorganisms, the respective impact of clonality and genetic exchange on <i>Leishmania</i> natural populations has been the object of lively debates since the early 1980s. The predominant clonal evolution (PCE) model states that genetic exchange i...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Michel Tibayrenc, Francisco J. Ayala
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	evolution clonality genetic recombination population structure aneuploidy molecular epidemiology Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/731437a180ce47f6af82cdc48226a38d
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:731437a180ce47f6af82cdc48226a38d
record_format	dspace
spelling	oai:doaj.org-article:731437a180ce47f6af82cdc48226a38d2021-11-25T18:25:46Z<i>Leishmania</i> and the Model of Predominant Clonal Evolution10.3390/microorganisms91124092076-2607https://doaj.org/article/731437a180ce47f6af82cdc48226a38d2021-11-01T00:00:00Zhttps://www.mdpi.com/2076-2607/9/11/2409https://doaj.org/toc/2076-2607As it is the case for other pathogenic microorganisms, the respective impact of clonality and genetic exchange on <i>Leishmania</i> natural populations has been the object of lively debates since the early 1980s. The predominant clonal evolution (PCE) model states that genetic exchange in these parasites’ natural populations may have a high relevance on an evolutionary scale, but is not sufficient to erase a persistent phylogenetic signal and the existence of bifurcating trees. Recent data based on high-resolution markers and genomic polymorphisms fully confirm the PCE model down to a microevolutionary level.Michel TibayrencFrancisco J. AyalaMDPI AGarticleevolutionclonalitygenetic recombinationpopulation structureaneuploidymolecular epidemiologyBiology (General)QH301-705.5ENMicroorganisms, Vol 9, Iss 2409, p 2409 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	evolution clonality genetic recombination population structure aneuploidy molecular epidemiology Biology (General) QH301-705.5
spellingShingle	evolution clonality genetic recombination population structure aneuploidy molecular epidemiology Biology (General) QH301-705.5 Michel Tibayrenc Francisco J. Ayala <i>Leishmania</i> and the Model of Predominant Clonal Evolution
description	As it is the case for other pathogenic microorganisms, the respective impact of clonality and genetic exchange on <i>Leishmania</i> natural populations has been the object of lively debates since the early 1980s. The predominant clonal evolution (PCE) model states that genetic exchange in these parasites’ natural populations may have a high relevance on an evolutionary scale, but is not sufficient to erase a persistent phylogenetic signal and the existence of bifurcating trees. Recent data based on high-resolution markers and genomic polymorphisms fully confirm the PCE model down to a microevolutionary level.
format	article
author	Michel Tibayrenc Francisco J. Ayala
author_facet	Michel Tibayrenc Francisco J. Ayala
author_sort	Michel Tibayrenc
title	<i>Leishmania</i> and the Model of Predominant Clonal Evolution
title_short	<i>Leishmania</i> and the Model of Predominant Clonal Evolution
title_full	<i>Leishmania</i> and the Model of Predominant Clonal Evolution
title_fullStr	<i>Leishmania</i> and the Model of Predominant Clonal Evolution
title_full_unstemmed	<i>Leishmania</i> and the Model of Predominant Clonal Evolution
title_sort	<i>leishmania</i> and the model of predominant clonal evolution
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/731437a180ce47f6af82cdc48226a38d
work_keys_str_mv	AT micheltibayrenc ileishmaniaiandthemodelofpredominantclonalevolution AT franciscojayala ileishmaniaiandthemodelofpredominantclonalevolution
_version_	1718411138470772736

<i>Leishmania</i> and the Model of Predominant Clonal Evolution

Ejemplares similares