Estimation of the impact of Fasciola hepatica infection on time taken for UK beef cattle to reach slaughter weight

Abstract Fasciolosis is common in UK beef cattle, but it is unclear at what levels liver fluke burdens cause production losses. This study aimed to address these uncertainties by estimating the impact of liver fluke infection on UK beef cattle productivity and investigating the use of diagnostic tes...

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Autores principales:	Stella Mazeri, Gustaf Rydevik, Ian Handel, Barend M. deC. Bronsvoort, Neil Sargison
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/7316c36432d94b9388a067a8cd9a2c62
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spelling	oai:doaj.org-article:7316c36432d94b9388a067a8cd9a2c622021-12-02T12:30:12ZEstimation of the impact of Fasciola hepatica infection on time taken for UK beef cattle to reach slaughter weight10.1038/s41598-017-07396-12045-2322https://doaj.org/article/7316c36432d94b9388a067a8cd9a2c622017-08-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-07396-1https://doaj.org/toc/2045-2322Abstract Fasciolosis is common in UK beef cattle, but it is unclear at what levels liver fluke burdens cause production losses. This study aimed to address these uncertainties by estimating the impact of liver fluke infection on UK beef cattle productivity and investigating the use of diagnostic tests in a quantitative manner. We built three linear regression models for slaughter age by weight and different measures of liver fluke status, while accounting for sex, breed, season, year and farm of origin. Data were sourced from Scotland’s largest red meat abattoir throughout 2013 and 2014. Our Meat Hygiene Service model estimated that cattle classified as having liver fluke damage had on average 10 days greater slaughter age than animals with no evidence of fasciolosis. Our liver fibrosis model estimated that the increase in slaughter age was more severe for higher fibrosis scores. Similarly, our burden model showed an increase in slaughter age for animals with as few as 1 to 10 parasites found in their livers. Lastly, we used receiver operating characteristic curves to show that serum antibody ELISA, copro-antigen ELISA and faecal egg counting can be useful in distinguishing between animals with and without production limiting levels of fasciolosis.Stella MazeriGustaf RydevikIan HandelBarend M. deC. BronsvoortNeil SargisonNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Stella Mazeri Gustaf Rydevik Ian Handel Barend M. deC. Bronsvoort Neil Sargison Estimation of the impact of Fasciola hepatica infection on time taken for UK beef cattle to reach slaughter weight
description	Abstract Fasciolosis is common in UK beef cattle, but it is unclear at what levels liver fluke burdens cause production losses. This study aimed to address these uncertainties by estimating the impact of liver fluke infection on UK beef cattle productivity and investigating the use of diagnostic tests in a quantitative manner. We built three linear regression models for slaughter age by weight and different measures of liver fluke status, while accounting for sex, breed, season, year and farm of origin. Data were sourced from Scotland’s largest red meat abattoir throughout 2013 and 2014. Our Meat Hygiene Service model estimated that cattle classified as having liver fluke damage had on average 10 days greater slaughter age than animals with no evidence of fasciolosis. Our liver fibrosis model estimated that the increase in slaughter age was more severe for higher fibrosis scores. Similarly, our burden model showed an increase in slaughter age for animals with as few as 1 to 10 parasites found in their livers. Lastly, we used receiver operating characteristic curves to show that serum antibody ELISA, copro-antigen ELISA and faecal egg counting can be useful in distinguishing between animals with and without production limiting levels of fasciolosis.
format	article
author	Stella Mazeri Gustaf Rydevik Ian Handel Barend M. deC. Bronsvoort Neil Sargison
author_facet	Stella Mazeri Gustaf Rydevik Ian Handel Barend M. deC. Bronsvoort Neil Sargison
author_sort	Stella Mazeri
title	Estimation of the impact of Fasciola hepatica infection on time taken for UK beef cattle to reach slaughter weight
title_short	Estimation of the impact of Fasciola hepatica infection on time taken for UK beef cattle to reach slaughter weight
title_full	Estimation of the impact of Fasciola hepatica infection on time taken for UK beef cattle to reach slaughter weight
title_fullStr	Estimation of the impact of Fasciola hepatica infection on time taken for UK beef cattle to reach slaughter weight
title_full_unstemmed	Estimation of the impact of Fasciola hepatica infection on time taken for UK beef cattle to reach slaughter weight
title_sort	estimation of the impact of fasciola hepatica infection on time taken for uk beef cattle to reach slaughter weight
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/7316c36432d94b9388a067a8cd9a2c62
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Estimation of the impact of Fasciola hepatica infection on time taken for UK beef cattle to reach slaughter weight

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