Identifying proteins bound to native mitotic ESC chromosomes reveals chromatin repressors are important for compaction
Epigenetic information is transmitted from mother to daughter cells through mitosis. Here, the authors isolate native chromosomes from metaphase-arrested cells and perform LC-MS/MS to identify chromosome-bound proteins in pluripotent stem cells during mitosis and reveal that PRC2, DNA methylation an...
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Auteurs principaux: | , , , , , , , , , , , , , , , , , , , |
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Format: | article |
Langue: | EN |
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Nature Portfolio
2020
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Accès en ligne: | https://doaj.org/article/73176d0dba7348dcb968ea5de1aa87c6 |
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