Tranexamic acid in otorhinolaryngology – A contemporary review

Tranexamic acid (TXA) is an anti-fibrinolytic agent which has been proven beneficial in multiple surgical specialties where significant bleeding can occur. Whilst it has been widely available for over 40 years its use within Otorhinolaryngology is still limited. Operations in Otorhinolaryngology are...

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Autores principales:	Jordan Fuzi, Gideon R. Budiono, Catherine Meller, Ian Jacobson
Formato:	article
Lenguaje:	EN
Publicado:	KeAi Communications Co., Ltd. 2021
Materias:	Tranexamic acid Otorhinolaryngology Surgery Bleeding RF1-547 RD1-811
Acceso en línea:	https://doaj.org/article/7321287b6a1d49ac9792f8c565505500
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spelling	oai:doaj.org-article:7321287b6a1d49ac9792f8c5655055002021-12-02T17:29:50ZTranexamic acid in otorhinolaryngology – A contemporary review2095-881110.1016/j.wjorl.2020.05.010https://doaj.org/article/7321287b6a1d49ac9792f8c5655055002021-10-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2095881120300974https://doaj.org/toc/2095-8811Tranexamic acid (TXA) is an anti-fibrinolytic agent which has been proven beneficial in multiple surgical specialties where significant bleeding can occur. Whilst it has been widely available for over 40 years its use within Otorhinolaryngology is still limited. Operations in Otorhinolaryngology are particularly varied with some such as tonsillectomy having the potential for significant life threatening bleeding. Other operations are performed within small confined surgical fields and even small amounts of bleeding can significantly detriment surgical field and increase technical difficulty and operative time. This review evaluated the current literature on the benefits of tranexamic acid within the field of Otorhinolaryngology and Head and Neck Surgery. Overall TXA was demonstrated to be a safe drug with no major adverse effects including thromboembolic events reported in any study. It has been shown to be of particular benefit in rhinology by improving surgical field, reducing operative time and reducing postoperative swelling and ecchymosis. The benefit in tonsillectomy is less clear and further studies are required to evaluate its potential use in the reduction of post tonsillectomy haemorrhage rates.Jordan FuziGideon R. BudionoCatherine MellerIan JacobsonKeAi Communications Co., Ltd.articleTranexamic acidOtorhinolaryngologySurgeryBleedingOtorhinolaryngologyRF1-547SurgeryRD1-811ENWorld Journal of Otorhinolaryngology-Head and Neck Surgery, Vol 7, Iss 4, Pp 328-337 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Tranexamic acid Otorhinolaryngology Surgery Bleeding Otorhinolaryngology RF1-547 Surgery RD1-811
spellingShingle	Tranexamic acid Otorhinolaryngology Surgery Bleeding Otorhinolaryngology RF1-547 Surgery RD1-811 Jordan Fuzi Gideon R. Budiono Catherine Meller Ian Jacobson Tranexamic acid in otorhinolaryngology – A contemporary review
description	Tranexamic acid (TXA) is an anti-fibrinolytic agent which has been proven beneficial in multiple surgical specialties where significant bleeding can occur. Whilst it has been widely available for over 40 years its use within Otorhinolaryngology is still limited. Operations in Otorhinolaryngology are particularly varied with some such as tonsillectomy having the potential for significant life threatening bleeding. Other operations are performed within small confined surgical fields and even small amounts of bleeding can significantly detriment surgical field and increase technical difficulty and operative time. This review evaluated the current literature on the benefits of tranexamic acid within the field of Otorhinolaryngology and Head and Neck Surgery. Overall TXA was demonstrated to be a safe drug with no major adverse effects including thromboembolic events reported in any study. It has been shown to be of particular benefit in rhinology by improving surgical field, reducing operative time and reducing postoperative swelling and ecchymosis. The benefit in tonsillectomy is less clear and further studies are required to evaluate its potential use in the reduction of post tonsillectomy haemorrhage rates.
format	article
author	Jordan Fuzi Gideon R. Budiono Catherine Meller Ian Jacobson
author_facet	Jordan Fuzi Gideon R. Budiono Catherine Meller Ian Jacobson
author_sort	Jordan Fuzi
title	Tranexamic acid in otorhinolaryngology – A contemporary review
title_short	Tranexamic acid in otorhinolaryngology – A contemporary review
title_full	Tranexamic acid in otorhinolaryngology – A contemporary review
title_fullStr	Tranexamic acid in otorhinolaryngology – A contemporary review
title_full_unstemmed	Tranexamic acid in otorhinolaryngology – A contemporary review
title_sort	tranexamic acid in otorhinolaryngology – a contemporary review
publisher	KeAi Communications Co., Ltd.
publishDate	2021
url	https://doaj.org/article/7321287b6a1d49ac9792f8c565505500
work_keys_str_mv	AT jordanfuzi tranexamicacidinotorhinolaryngologyacontemporaryreview AT gideonrbudiono tranexamicacidinotorhinolaryngologyacontemporaryreview AT catherinemeller tranexamicacidinotorhinolaryngologyacontemporaryreview AT ianjacobson tranexamicacidinotorhinolaryngologyacontemporaryreview
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Tranexamic acid in otorhinolaryngology – A contemporary review

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