Cancer drivers and clonal dynamics in acute lymphoblastic leukaemia subtypes

Cancer drivers and clonal dynamics in acute lymphoblastic leukaemia subtypes

Abstract To obtain a comprehensive picture of composite genetic driver events and clonal dynamics in subtypes of paediatric acute lymphoblastic leukaemia (ALL) we analysed tumour-normal whole genome sequencing and expression data from 361 newly diagnosed patients. We report the identification of bot...

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Autores principales: James B. Studd, Alex J. Cornish, Phuc H. Hoang, Philip Law, Ben Kinnersley, Richard Houlston
Formato: article
Lenguaje:EN
Publicado: Nature Publishing Group 2021
Materias:
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
Acceso en línea:https://doaj.org/article/732acc4b856f474288360cfb1b5493f3
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