Restoration of visual function by transplantation of optogenetically engineered photoreceptors
A challenge in cell therapy for photoreceptor degeneration is inducing the grafted cells to grow and maintain light sensitive outer segments. Here, the authors use optogenetics to circumvent this problem and restore visual function in blind mice.
Guardado en:
Autores principales: | Marcela Garita-Hernandez, Maruša Lampič, Antoine Chaffiol, Laure Guibbal, Fiona Routet, Tiago Santos-Ferreira, Sylvia Gasparini, Oliver Borsch, Giuliana Gagliardi, Sacha Reichman, Serge Picaud, José-Alain Sahel, Olivier Goureau, Marius Ader, Deniz Dalkara, Jens Duebel |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2019
|
Materias: | |
Acceso en línea: | https://doaj.org/article/732d87294a534f1ab4fe044f1dcd7507 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Retinal transplantation of photoreceptors results in donor–host cytoplasmic exchange
por: Tiago Santos-Ferreira, et al.
Publicado: (2016) -
Functional ultrasound imaging of the spreading activity following optogenetic stimulation of the rat visual cortex
por: M. Provansal, et al.
Publicado: (2021) -
Optogenetic therapy: high spatiotemporal resolution and pattern discrimination compatible with vision restoration in non-human primates
por: Gregory Gauvain, et al.
Publicado: (2021) -
Stress reaction in outer segments of photoreceptors after blue light irradiation.
por: Cora Roehlecke, et al.
Publicado: (2013) -
In vitro expanded stem cells from the developing retina fail to generate photoreceptors but differentiate into myelinating oligodendrocytes.
por: Magdalena Czekaj, et al.
Publicado: (2012)