Fine specificity and molecular competition in SLAM family receptor signalling.

SLAM family receptors regulate activation and inhibition in immunity through recruitment of activating and inhibitory SH2 domain containing proteins to immunoreceptor tyrosine based switch motifs (ITSMs). Binding of the adaptors, SAP and EAT-2 to ITSMs in the cytoplasmic regions of SLAM family recep...

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Auteurs principaux: Timothy J Wilson, Lee I Garner, Clive Metcalfe, Elliott King, Stefanie Margraf, Marion H Brown
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2014
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R
Q
Accès en ligne:https://doaj.org/article/732f6e88f0534aa89a42b1145813c61a
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