Vitamin D status, filaggrin genotype, and cardiovascular risk factors: a Mendelian randomization approach.

Vitamin D status, filaggrin genotype, and cardiovascular risk factors: a Mendelian randomization approach.

<h4>Background</h4>Vitamin D deficiency is associated with increased cardiovascular disease risk in observational studies. Whether these associations are causal is not clear. Loss-of-function mutations in the filaggrin gene result in up to 10% higher serum vitamin D concentrations, suppo...

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Auteurs principaux: Tea Skaaby, Lise Lotte Nystrup Husemoen, Torben Martinussen, Jacob P Thyssen, Michael Melgaard, Betina Heinsbæk Thuesen, Charlotta Pisinger, Torben Jørgensen, Jeanne D Johansen, Torkil Menné, Berit Carlsen, Pal B Szecsi, Steen Stender, Runa Vavia Fenger, Mogens Fenger, Allan Linneberg
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2013
Sujets:
Medicine
R
Science
Q
Accès en ligne:https://doaj.org/article/732fda88818e4d3390ac9057343a140b
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https://doaj.org/article/732fda88818e4d3390ac9057343a140b

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