Tracking oxidation-induced alterations in fibrin clot formation by NMR-based methods

Abstract Plasma fibrinogen is an important coagulation factor and susceptible to post-translational modification by oxidants. We have reported impairment of fibrin polymerization after exposure to hypochlorous acid (HOCl) and increased methionine oxidation of fibrinogen in severely injured trauma pa...

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Autores principales: Wai-Hoe Lau, Nathan J. White, Tsin-Wen Yeo, Russell L. Gruen, Konstantin Pervushin
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/7330f566b0e941b3a178951811845285
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